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2017 ; 17
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gab.com Text
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English Wikipedia
Label-Free Biological and Chemical Sensing Using Whispering Gallery Mode Optical
Resonators: Past, Present, and Future
#MMPMID28282881
Su J
Sensors (Basel)
2017[Mar]; 17
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): ä PMID28282881
show ga
Sensitive and rapid label-free biological and chemical sensors are needed for a
wide variety of applications including early disease diagnosis and prognosis, the
monitoring of food and water quality, as well as the detection of bacteria and
viruses for public health concerns and chemical threat sensing. Whispering
gallery mode optical resonator based sensing is a rapidly developing field due to
the high sensitivity and speed of these devices as well as their label-free
nature. Here, we describe the history of whispering gallery mode optical
resonator sensors, the principles behind detection, the latest developments in
the fields of biological and chemical sensing, current challenges toward
widespread adoption of these devices, and an outlook for the future. In addition,
we evaluate the performance capabilities of these sensors across three key
parameters: sensitivity, selectivity, and speed.