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10.1182/blood-2016-09-740431 http://scihub22266oqcxt.onion/10.1182/blood-2016-09-740431 C5374290!5374290!28153825     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Blood 2017 ; 129 (13): 1747-52 Nephropedia Template TP {{tp|p=28153825|t=2017. Tissue tolerance: a distinct concept to control acute GVHD severity |pdf=|usr=}}{{28153825}} gab.com Text Tissue tolerance: a distinct concept to control acute GVHD severity JO: Blood http://www.kidney.de/pget.php?&tw=1&pmid=28153825 #FOAvip Target tissue damage occurs as a consequence of pathological immune responses following allogeneic stem cell transplantation resulting in acute graft-versus-host disease (GVHD). Among those who study infections in plants, it is well recognized that tissues play a distinct role from the immune system in mediating disease severity. Recently, this has also been appreciated in mammals. However, the severity of immunopathology in the context of alloimmune diseases such as acute GVHD has been mainly understood and managed by direct targeting of immune cells to generate immune tolerance. The role of tissue-intrinsic factors that might contribute to regulation of acute GVHD severity has been largely overlooked. Here, we introduce the concept of ?tissue tolerance? to discuss the tissue-specific programs that contribute to target tissue resilience, repair, and regeneration, and mitigate severity of acute GVHD without altering the load or function of alloreactive immune cells. Twit Text FOAVip Tissue tolerance: a distinct concept to control acute GVHD severity ????Blood http://www.kidney.de/pget.php?&tw=1&pmid=28153825 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28153825 #FOAvip English Wikipedia <ref>{{Cite pmid|28153825}}</ref> Tissue tolerance: a distinct concept to control acute GVHD severity #MMPMID28153825 Wu SR; Reddy P Blood 2017[Mar]; 129 (13): 1747-52 PMID28153825show ga Target tissue damage occurs as a consequence of pathological immune responses following allogeneic stem cell transplantation resulting in acute graft-versus-host disease (GVHD). Among those who study infections in plants, it is well recognized that tissues play a distinct role from the immune system in mediating disease severity. Recently, this has also been appreciated in mammals. However, the severity of immunopathology in the context of alloimmune diseases such as acute GVHD has been mainly understood and managed by direct targeting of immune cells to generate immune tolerance. The role of tissue-intrinsic factors that might contribute to regulation of acute GVHD severity has been largely overlooked. Here, we introduce the concept of ?tissue tolerance? to discuss the tissue-specific programs that contribute to target tissue resilience, repair, and regeneration, and mitigate severity of acute GVHD without altering the load or function of alloreactive immune cells. äTissue tolerance: a distinct concept to control acute GVHD severity (epmc).pdf DeepDyve Pubget Overpricing