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10.1073/pnas.1701464114 http://scihub22266oqcxt.onion/10.1073/pnas.1701464114 C5373387!5373387!28270600     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 265.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Proc+Natl+Acad+Sci+U+S+A 2017 ; 114 (12): 3121-6 Nephropedia Template TP {{tp|p=28270600|t=2017. Diverse regulation of mammary epithelial growth and branching morphogenesis through noncanonical Wnt signaling |pdf=|usr=}}{{28270600}} gab.com Text Diverse regulation of mammary epithelial growth and branching morphogenesis through noncanonical Wnt signaling JO: Proc Natl Acad Sci U S A http://www.kidney.de/pget.php?&tw=1&pmid=28270600 #FOAvip The extracellular signals that regulate cell growth and tissue rearrangements during organogenesis are still poorly understood. One large family of secreted signaling molecules, called wingless-type MMTV integration site family member (WNTs), governs many of these processes by controlling cell?cell interactions. Here, we show that two closely related members of the WNT superfamily influence the development of the mammary gland by signaling through different tyrosine kinase receptors. WNT5A enhances the growth of mammary stem/progenitor cells while restricting the process of branching morphogenesis. In contrast, WNT5B represses mammary stem/progenitor cell proliferation through a different receptor. Together, the distinct actions of these highly homologous extracellular cues regulate the developmental processes that supply cells and shape tissues during periods of rapid growth. Twit Text FOAVip Diverse regulation of mammary epithelial growth and branching morphogenesis through noncanonical Wnt signaling ????Proc Natl Acad Sci U S A http://www.kidney.de/pget.php?&tw=1&pmid=28270600 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28270600 #FOAvip English Wikipedia <ref>{{Cite pmid|28270600}}</ref> Diverse regulation of mammary epithelial growth and branching morphogenesis through noncanonical Wnt signaling #MMPMID28270600 Kessenbrock K; Smith P; Steenbeek SC; Pervolarakis N; Kumar R; Minami Y; Goga A; Hinck L; Werb Z Proc Natl Acad Sci U S A 2017[Mar]; 114 (12): 3121-6 PMID28270600show ga The extracellular signals that regulate cell growth and tissue rearrangements during organogenesis are still poorly understood. One large family of secreted signaling molecules, called wingless-type MMTV integration site family member (WNTs), governs many of these processes by controlling cell?cell interactions. Here, we show that two closely related members of the WNT superfamily influence the development of the mammary gland by signaling through different tyrosine kinase receptors. WNT5A enhances the growth of mammary stem/progenitor cells while restricting the process of branching morphogenesis. In contrast, WNT5B represses mammary stem/progenitor cell proliferation through a different receptor. Together, the distinct actions of these highly homologous extracellular cues regulate the developmental processes that supply cells and shape tissues during periods of rapid growth. äDiverse regulation of mammary epithelial growth and branching morphoge(epmc).pdf DeepDyve Pubget Overpricing