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2017 ; 8
(ä): 374
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Contemporary Understanding of miRNA-Based Regulation of Secondary Metabolites
Biosynthesis in Plants
#MMPMID28424705
Gupta OP
; Karkute SG
; Banerjee S
; Meena NL
; Dahuja A
Front Plant Sci
2017[]; 8
(ä): 374
PMID28424705
show ga
Plant's secondary metabolites such as flavonoids, terpenoids, and alkaloids etc.
are known for their role in the defense against various insects-pests of plants
and for medicinal benefits in human. Due to the immense biological importance of
these phytochemicals, understanding the regulation of their biosynthetic pathway
is crucial. In the recent past, advancement in the molecular technologies has
enabled us to better understand the proteins, enzymes, genes, etc. involved in
the biosynthetic pathway of the secondary metabolites. miRNAs are magical, tiny,
non-coding ribonucleotides that function as critical regulators of gene
expression in eukaryotes. Despite the accumulated knowledge of the miRNA-mediated
regulation of several processes, the involvement of miRNAs in regulating
secondary plant product biosynthesis is still poorly understood. Here, we
summarize the recent progress made in the area of identification and
characterizations of miRNAs involved in regulating the biosynthesis of secondary
metabolites in plants and discuss the future perspectives for designing the
viable strategies for their targeted manipulation.