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2017 ; 5
(6
): ä Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Physiological and biochemical changes associated with acute experimental
dehydration in the desert adapted mouse, Peromyscus eremicus
#MMPMID28330954
Kordonowy L
; Lombardo KD
; Green HL
; Dawson MD
; Bolton EA
; LaCourse S
; MacManes MD
Physiol Rep
2017[Mar]; 5
(6
): ä PMID28330954
show ga
Characterizing traits critical for adaptation to a given environment is an
important first step in understanding how phenotypes evolve. How animals adapt to
the extreme heat and aridity commonplace to deserts is an exceptionally
interesting example of these processes, and has been the focus of study for
decades. In contrast to those studies, where experiments are conducted on either
wild animals or captive animals held in non-desert conditions, the study
described here leverages a unique environmental chamber that replicates desert
conditions for captive Peromyscus eremicus (cactus mouse). Here, we establish
baseline values for daily water intake and for serum electrolytes, as well as the
response of these variables to acute experimental dehydration. In brief,
P eremicus daily water intake is very low. Its serum electrolytes are distinct
from many previously studied animals, and its response to acute dehydration is
profound, though not suggestive of renal impairment, which is atypical of
mammals.