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10.4049/jimmunol.1601781 http://scihub22266oqcxt.onion/10.4049/jimmunol.1601781 C5369026!5369026!28213503     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 278.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 278.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 278.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 278.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 278.79999999999995 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 312.4 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 312.4 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 312.4 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Immunol 2017 ; 198 (7): 2906-15 Nephropedia Template TP {{tp|p=28213503|t=2017. INHIBITION OF INFLAMMATORY GENE TRANSCRIPTION BY IL-10 IS ASSOCIATED WITH RAPID SUPPRESSION OF LPS-INDUCED ENHANCER ACTIVATION1: Suppression of LPS-Induced Enhancer Activation by IL-10 |pdf=|usr=}}{{28213503}} gab.com Text INHIBITION OF INFLAMMATORY GENE TRANSCRIPTION BY IL-10 IS ASSOCIATED WITH RAPID SUPPRESSION OF LPS-INDUCED ENHANCER ACTIVATION1: Suppression of LPS-Induced Enhancer Activation by IL-10 JO: J Immunol http://www.kidney.de/pget.php?&tw=1&pmid=28213503 #FOAvip IL-10 limits the magnitude of inflammatory gene expression following microbial stimuli and is essential to prevent inflammatory disease, however, the molecular basis for IL-10 mediated inhibition remains elusive. Using a genome-wide approach we demonstrate that inhibition of transcription is the primary mechanism for IL-10-mediated suppression in LPS-stimulated macrophages, and that inhibited genes can be divided into two clusters. Genes in the first cluster are inhibited only if IL-10 is included early in the course of LPS stimulation and is strongly enriched for interferon-inducible genes. Genes in the second cluster can be rapidly suppressed by IL-10 even after transcription is initiated, and this is associated with suppression of LPS-induced enhancer activation. Interestingly, the ability of IL-10 to rapidly suppress active transcription exhibits a delay following LPS stimulation. Thus, a key pathway for IL-10 mediated suppression involves rapid inhibition of enhancer function during the secondary phase of the response to LPS. Twit Text FOAVip INHIBITION OF INFLAMMATORY GENE TRANSCRIPTION BY IL-10 IS ASSOCIATED WITH RAPID SUPPRESSION OF LPS-INDUCED ENHANCER ACTIVATION1: Suppression of LPS-Induced Enhancer Activation by IL-10 ????J Immunol http://www.kidney.de/pget.php?&tw=1&pmid=28213503 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28213503 #FOAvip English Wikipedia <ref>{{Cite pmid|28213503}}</ref> INHIBITION OF INFLAMMATORY GENE TRANSCRIPTION BY IL-10 IS ASSOCIATED WITH RAPID SUPPRESSION OF LPS-INDUCED ENHANCER ACTIVATION1: Suppression of LPS-Induced Enhancer Activation by IL-10 #MMPMID28213503 Conaway EA; de Oliveira DC; McInnis CM; Snapper SB; Horwitz BH J Immunol 2017[Apr]; 198 (7): 2906-15 PMID28213503show ga IL-10 limits the magnitude of inflammatory gene expression following microbial stimuli and is essential to prevent inflammatory disease, however, the molecular basis for IL-10 mediated inhibition remains elusive. Using a genome-wide approach we demonstrate that inhibition of transcription is the primary mechanism for IL-10-mediated suppression in LPS-stimulated macrophages, and that inhibited genes can be divided into two clusters. Genes in the first cluster are inhibited only if IL-10 is included early in the course of LPS stimulation and is strongly enriched for interferon-inducible genes. Genes in the second cluster can be rapidly suppressed by IL-10 even after transcription is initiated, and this is associated with suppression of LPS-induced enhancer activation. Interestingly, the ability of IL-10 to rapidly suppress active transcription exhibits a delay following LPS stimulation. Thus, a key pathway for IL-10 mediated suppression involves rapid inhibition of enhancer function during the secondary phase of the response to LPS. äINHIBITION OF INFLAMMATORY GENE TRANSCRIPTION BY IL-10 IS ASSOCIATED W(epmc).pdf DeepDyve Pubget Overpricing