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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 BMC+Neurol
2017 ; 17
(1
): 62
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Healthcare resource use and costs of multiple sclerosis patients in Germany
before and during fampridine treatment
#MMPMID28347283
Ziemssen T
; Prosser C
; Haas JS
; Lee A
; Braun S
; Landsman-Blumberg P
; Kempel A
; Gleißner E
; Patel S
; Huang MY
BMC Neurol
2017[Mar]; 17
(1
): 62
PMID28347283
show ga
BACKGROUND: Multiple sclerosis (MS) patients often suffer from gait impairment
and fampridine is indicated to medically improve walking ability in this
population. Patient characteristics, healthcare resource use, and costs of MS
patients on fampridine treatment for 12 months in Germany were analyzed. METHODS:
A retrospective claims database analysis was conducted including MS patients who
initiated fampridine treatment (index date) between July 2011 and December 2013.
Continuous insurance enrollment during 12 months pre- and post-index date was
required, as was at least 1 additional fampridine prescription in the fourth
quarter after the index date. Patient characteristics were evaluated and pre- vs
post-index MS-related healthcare utilization and costs were compared. RESULTS: A
total of 562 patients were included in this study. The mean (standard deviation
[SD]) age was 50.5 (9.8) years and 63% were female. In the treatment period,
almost every patient had at least 1 MS-related outpatient visit, 24% were
hospitalized due to MS, and 79% utilized MS-specific physical therapy in addition
to the fampridine treatment. Total MS-related healthcare costs were significantly
higher in the fampridine treatment period than in the period prior to fampridine
initiation (?17,392 vs ?10,960, P?0.001). While this difference was driven
primarily by prescription costs, MS-related inpatient costs were lower during
fampridine treatment (?1,333 vs ?1,565, P?0.001). CONCLUSIONS: Physical therapy
is mainly used concomitant to fampridine treatment. While healthcare costs were
higher during fampridine treatment compared to the pre-treatment period,
inpatient costs were lower. Further research is necessary to better understand
the fampridine influence.
|4-Aminopyridine/economics/*therapeutic use
[MESH]
|Adult
[MESH]
|Female
[MESH]
|Germany
[MESH]
|Health Care Costs/*statistics & numerical data
[MESH]