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10.3390/genes8030088 http://scihub22266oqcxt.onion/10.3390/genes8030088 C5368692!5368692!28245597     free     free     free       Genes+(Basel) 2017 ; 8 (3): ä Nephropedia Template TP {{tp|p=28245597|t=2017. MYC in Regulating Immunity: Metabolism and Beyond |pdf=|usr=}}{{28245597}} gab.com Text MYC in Regulating Immunity: Metabolism and Beyond JO: Genes (Basel) http://www.kidney.de/pget.php?&tw=1&pmid=28245597 #FOAvip Myelocytomatosis oncogene (MYC) family members, including cellular MYC (c-Myc), neuroblastoma derived MYC (MYCN), and lung carcinoma derived MYC (MYCL), have all been implicated as key oncogenic drivers in a broad range of human cancers. Beyond cancer, MYC plays an important role in other physiological and pathological processes, namely immunity and immunological diseases. MYC largely functions as a transcription factor that promotes the expression of numerous target genes to coordinate death, proliferation, and metabolism at the cellular, tissue, and organismal levels. It has been shown that the expression of MYC family members is tightly regulated in immune cells during development or upon immune stimulations. Emerging evidence suggests that MYC family members play essential roles in regulating the development, differentiation and activation of immune cells. Through driving the expression of a broad range of metabolic genes in immune cells, MYC family members coordinate metabolic programs to support immune functions. Here, we discuss our understanding of MYC biology in immune system and how modulation of MYC impacts immune metabolism and responses. Twit Text FOAVip MYC in Regulating Immunity: Metabolism and Beyond ????Genes (Basel) http://www.kidney.de/pget.php?&tw=1&pmid=28245597 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28245597 #FOAvip English Wikipedia <ref>{{Cite pmid|28245597}}</ref> MYC in Regulating Immunity: Metabolism and Beyond #MMPMID28245597 Gnanaprakasam JR; Wang R Genes (Basel) 2017[Mar]; 8 (3): ä PMID28245597show ga Myelocytomatosis oncogene (MYC) family members, including cellular MYC (c-Myc), neuroblastoma derived MYC (MYCN), and lung carcinoma derived MYC (MYCL), have all been implicated as key oncogenic drivers in a broad range of human cancers. Beyond cancer, MYC plays an important role in other physiological and pathological processes, namely immunity and immunological diseases. MYC largely functions as a transcription factor that promotes the expression of numerous target genes to coordinate death, proliferation, and metabolism at the cellular, tissue, and organismal levels. It has been shown that the expression of MYC family members is tightly regulated in immune cells during development or upon immune stimulations. Emerging evidence suggests that MYC family members play essential roles in regulating the development, differentiation and activation of immune cells. Through driving the expression of a broad range of metabolic genes in immune cells, MYC family members coordinate metabolic programs to support immune functions. Here, we discuss our understanding of MYC biology in immune system and how modulation of MYC impacts immune metabolism and responses. äMYC in Regulating Immunity: Metabolism and Beyond (epmc).pdf DeepDyve Pubget Overpricing