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10.1007/s00467-017-3584-9

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C5368203!5368203!28194574
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suck abstract from ncbi


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pmid28194574      Pediatr+Nephrol 2017 ; 32 (5): 893-6
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  • Tolvaptan treatment for severe neonatal autosomal-dominant polycystic kidney disease #MMPMID28194574
  • Gilbert RD; Evans H; Olalekan K; Nagra A; Haq MR; Griffiths M
  • Pediatr Nephrol 2017[]; 32 (5): 893-6 PMID28194574show ga
  • Background: Severe neonatal autosomal-dominant polycystic kidney disease (ADPKD) is rare and easily confused with recessive PKD. Managing such infants is difficult and often unsuccessful. Case diagnosis/treatment: A female infant with massive renal enlargement, respiratory compromise and hyponatraemia was treated with the arginine vasopressin receptor 2 antagonist tolvaptan. This resolved hyponatraemia, and there was no further increase in renal size. Conclusion: Tolvaptan may be a useful treatment for severe neonatal PKD.
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