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10.3389/fphar.2017.00153 http://scihub22266oqcxt.onion/10.3389/fphar.2017.00153 C5368180!5368180!28400729     free     free     free Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Front+Pharmacol 2017 ; 8 (ä): ä Nephropedia Template TP {{tp|p=28400729|t=2017. Prostate Cancer Stem Cells and Nanotechnology: A Focus on Wnt Signaling |pdf=|usr=}}{{28400729}} gab.com Text Prostate Cancer Stem Cells and Nanotechnology: A Focus on Wnt Signaling JO: Front Pharmacol http://www.kidney.de/pget.php?&tw=1&pmid=28400729 #FOAvip Prostate cancer is the most common cancer among men worldwide. However, current treatments for prostate cancer patients in advanced stage often fail because of relapse. Prostate cancer stem cells (PCSCs) are resistant to most standard therapies, and are considered to be a major mechanism of cancer metastasis and recurrence. In this review, we summarized current understanding of PCSCs and their self-renewal signaling pathways with a specific focus on Wnt signaling. Although multiple Wnt inhibitors have been developed to target PCSCs, their application is still limited by inefficient delivery and toxicity in vivo. Recently, nanotechnology has opened a new avenue for cancer drug delivery, which significantly increases specificity and reduces toxicity. These nanotechnology-based drug delivery methods showed great potential in targeting PCSCs. Here, we summarized current advancement of nanotechnology-based therapeutic strategies for targeting PCSCs and highlighted the challenges and perspectives in designing future therapies to eliminate PCSCs. Twit Text FOAVip Prostate Cancer Stem Cells and Nanotechnology: A Focus on Wnt Signaling ????Front Pharmacol http://www.kidney.de/pget.php?&tw=1&pmid=28400729 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28400729 #FOAvip English Wikipedia <ref>{{Cite pmid|28400729}}</ref> Prostate Cancer Stem Cells and Nanotechnology: A Focus on Wnt Signaling #MMPMID28400729 Qin W; Zheng Y; Qian BZ; Zhao M Front Pharmacol 2017[]; 8 (ä): ä PMID28400729show ga Prostate cancer is the most common cancer among men worldwide. However, current treatments for prostate cancer patients in advanced stage often fail because of relapse. Prostate cancer stem cells (PCSCs) are resistant to most standard therapies, and are considered to be a major mechanism of cancer metastasis and recurrence. In this review, we summarized current understanding of PCSCs and their self-renewal signaling pathways with a specific focus on Wnt signaling. Although multiple Wnt inhibitors have been developed to target PCSCs, their application is still limited by inefficient delivery and toxicity in vivo. Recently, nanotechnology has opened a new avenue for cancer drug delivery, which significantly increases specificity and reduces toxicity. These nanotechnology-based drug delivery methods showed great potential in targeting PCSCs. Here, we summarized current advancement of nanotechnology-based therapeutic strategies for targeting PCSCs and highlighted the challenges and perspectives in designing future therapies to eliminate PCSCs. äProstate Cancer Stem Cells and Nanotechnology: A Focus on Wnt Signalin(epmc).pdf DeepDyve Pubget Overpricing