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10.4049/jimmunol.1602031 http://scihub22266oqcxt.onion/10.4049/jimmunol.1602031 C5363282!5363282!28320913     free     free     free       J+Immunol 2017 ; 198 (7): 2527-33 Nephropedia Template TP {{tp|p=28320913|t=2017. Relationship between CD4 Tregs and anergy in vivo |pdf=|usr=}}{{28320913}} gab.com Text Relationship between CD4 Tregs and anergy in vivo JO: J Immunol http://www.kidney.de/pget.php?&tw=1&pmid=28320913 #FOAvip Selective suppression of effector CD4+ T cell functions is necessary to prevent immune cell-mediated damage to healthy tissues. This appears especially true during pregnancy or in individuals predisposed to autoimmunity. Foxp3+ regulatory T (Treg) cells and induction of anergy, an acquired state of T cell functional unresponsiveness in Foxp3? cells, have both been implicated as mechanisms to suppress dangerous immune responses to tissue-restricted self antigens. Anergic CD4+ T cells and Treg cells share a number of phenotypic and mechanistic traits?including the expression of CD73 and folate receptor 4 (FR4), and the epigenetic modification of Treg cell signature genes?and an interesting relationship between these two subsets has recently emerged. In this review, we will compare and contrast these two subsets as well as explore the role of anergy in the generation of peripheral Treg cells. Twit Text FOAVip Relationship between CD4 Tregs and anergy in vivo ????J Immunol http://www.kidney.de/pget.php?&tw=1&pmid=28320913 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28320913 #FOAvip English Wikipedia <ref>{{Cite pmid|28320913}}</ref> Relationship between CD4 Tregs and anergy in vivo #MMPMID28320913 Kalekar LA; Mueller DL J Immunol 2017[Apr]; 198 (7): 2527-33 PMID28320913show ga Selective suppression of effector CD4+ T cell functions is necessary to prevent immune cell-mediated damage to healthy tissues. This appears especially true during pregnancy or in individuals predisposed to autoimmunity. Foxp3+ regulatory T (Treg) cells and induction of anergy, an acquired state of T cell functional unresponsiveness in Foxp3? cells, have both been implicated as mechanisms to suppress dangerous immune responses to tissue-restricted self antigens. Anergic CD4+ T cells and Treg cells share a number of phenotypic and mechanistic traits?including the expression of CD73 and folate receptor 4 (FR4), and the epigenetic modification of Treg cell signature genes?and an interesting relationship between these two subsets has recently emerged. In this review, we will compare and contrast these two subsets as well as explore the role of anergy in the generation of peripheral Treg cells. äRelationship between CD4 Tregs and anergy in vivo (epmc).pdf DeepDyve Pubget Overpricing