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10.1007/s12079-016-0372-4

http://scihub22266oqcxt.onion/10.1007/s12079-016-0372-4
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C5362578!5362578!28000149
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suck abstract from ncbi


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pmid28000149      J+Cell+Commun+Signal 2017 ; 11 (1): 77-8
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  • Fibro/adipogenic progenitors safeguard themselves: a novel mechanism to reduce fibrosis is discovered #MMPMID28000149
  • Contreras O; Brandan E
  • J Cell Commun Signal 2017[Mar]; 11 (1): 77-8 PMID28000149show ga
  • PDGFR? regulates several cellular processes, and exacerbated PDGF signaling cause fibrosis in different tissues. Different research groups have shown that fibro/adipogenic progenitors (FAPs) are responsible for pathological fibrosis found in skeletal muscle disorders. Rando?s Lab describes that an intronic polyadenylation of Pdgfra regulates FAPs activity, and therefore fibrosis. This discovery opens a new potential target for treating fibrosis.
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