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10.18632/oncotarget.14392 http://scihub22266oqcxt.onion/10.18632/oncotarget.14392 C5362538!5362538!28052018     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Oncotarget 2017 ; 8 (9): 15961-70 Nephropedia Template TP {{tp|p=28052018|t=2017. Targeting microRNAs: a new action mechanism of natural compounds |pdf=|usr=}}{{28052018}} gab.com Text Targeting microRNAs: a new action mechanism of natural compounds JO: Oncotarget http://www.kidney.de/pget.php?&tw=1&pmid=28052018 #FOAvip Unlike genetics, epigenetics involves the modification of genome without changes in DNA sequences, including DNA methylation, histone modification, chromatin remodeling and noncoding RNA regulation. MicroRNA (miRNA), a member of noncoding RNAs superfamily, participates in RNA interference through a unique mechanism. Currently, microRNAs have been found to be regulated by some natural compounds. Through altering the expression of miRNAs and influencing the downstream signaling pathways or target genes, several natural compounds exhibit its bioactivity in the prevention, diagnosis, therapy, prognosis and drug resistance of human diseases, such as cancer. In this review, several natural compounds and their studies about miRNA-related action mechanism were summarized. These studies provide a new insight into action mechanism by which natural compound exerts its bioactivity and a novel treatment strategy, demonstrating natural compound a promising remedy for clinical treatments. Twit Text FOAVip Targeting microRNAs: a new action mechanism of natural compounds ????Oncotarget http://www.kidney.de/pget.php?&tw=1&pmid=28052018 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28052018 #FOAvip English Wikipedia <ref>{{Cite pmid|28052018}}</ref> Targeting microRNAs: a new action mechanism of natural compounds #MMPMID28052018 Lin Q; Ma L; Liu Z; Yang Z; Wang J; Liu J; Jiang G Oncotarget 2017[Feb]; 8 (9): 15961-70 PMID28052018show ga Unlike genetics, epigenetics involves the modification of genome without changes in DNA sequences, including DNA methylation, histone modification, chromatin remodeling and noncoding RNA regulation. MicroRNA (miRNA), a member of noncoding RNAs superfamily, participates in RNA interference through a unique mechanism. Currently, microRNAs have been found to be regulated by some natural compounds. Through altering the expression of miRNAs and influencing the downstream signaling pathways or target genes, several natural compounds exhibit its bioactivity in the prevention, diagnosis, therapy, prognosis and drug resistance of human diseases, such as cancer. In this review, several natural compounds and their studies about miRNA-related action mechanism were summarized. These studies provide a new insight into action mechanism by which natural compound exerts its bioactivity and a novel treatment strategy, demonstrating natural compound a promising remedy for clinical treatments. äTargeting microRNAs: a new action mechanism of natural compounds (epmc).pdf DeepDyve Pubget Overpricing