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10.12659/msm.903248 http://scihub22266oqcxt.onion/10.12659/msm.903248 C5362190!5362190 !28289272     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=28289272 &cmd=llinks): Failed to open stream: HTTP request failed! 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High Expression of Angiogenic Factor with G-Patch and FHA Domain1 (AGGF1) Predicts Poor Prognosis in Gastric Cancer |pdf=|usr=}}{{28289272 }} gab.com Text High Expression of Angiogenic Factor with G-Patch and FHA Domain1 (AGGF1) Predicts Poor Prognosis in Gastric Cancer JO: Med Sci Monit http://www.kidney.de/pget.php?&tw=1&pmid=28289272 #FOAvip BACKGROUND Angiogenic factor with G-patch and FHA domain1 (AGGF1 or VG5Q) is a newly identified human angiogenic factor. The aim of this study was to explore AGGF1 expression level in gastric cancer and detect its correlation with the prognosis. MATERIAL AND METHODS Immunohistochemistry was performed to detect AGGF1 level in gastric cancer and its adjacent noncancerous samples of 198 cases, and the relationships among the expression levels of AGGF1, vascular endothelial growth factor (VEGF), and prognosis were analyzed. RESULTS Expression of AGGF1 in gastric cancer samples was significantly higher than that in adjacent noncancerous samples (P<0.001). The overall survival rate (OS) of patients with high AGGF1 expression was significantly lower than that of patients with low AGGF1 expression (P=0.000). The Cox model analysis demonstrated that expression of AGGF1 was an independent biomarker for prediction of patients' survival in gastric cancer. CONCLUSIONS High expression of AGGF1 predicts poor prognosis in gastric cancer patients. AGGF1 can be used as an independent factor to predict postoperative survival of patients with gastric cancer. Twit Text FOAVip High Expression of Angiogenic Factor with G-Patch and FHA Domain1 (AGGF1) Predicts Poor Prognosis in Gastric Cancer ????Med Sci Monit http://www.kidney.de/pget.php?&tw=1&pmid=28289272 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28289272 #FOAvip English Wikipedia <ref>{{Cite pmid|28289272 }}</ref> High Expression of Angiogenic Factor with G-Patch and FHA Domain1 (AGGF1) Predicts Poor Prognosis in Gastric Cancer #MMPMID28289272 Yao HH ; Wang BJ ; Wu Y ; Huang Q Med Sci Monit 2017[Mar]; 23 (ä): 1286-1294 PMID28289272 show ga BACKGROUND Angiogenic factor with G-patch and FHA domain1 (AGGF1 or VG5Q) is a newly identified human angiogenic factor. The aim of this study was to explore AGGF1 expression level in gastric cancer and detect its correlation with the prognosis. MATERIAL AND METHODS Immunohistochemistry was performed to detect AGGF1 level in gastric cancer and its adjacent noncancerous samples of 198 cases, and the relationships among the expression levels of AGGF1, vascular endothelial growth factor (VEGF), and prognosis were analyzed. RESULTS Expression of AGGF1 in gastric cancer samples was significantly higher than that in adjacent noncancerous samples (P<0.001). The overall survival rate (OS) of patients with high AGGF1 expression was significantly lower than that of patients with low AGGF1 expression (P=0.000). The Cox model analysis demonstrated that expression of AGGF1 was an independent biomarker for prediction of patients' survival in gastric cancer. CONCLUSIONS High expression of AGGF1 predicts poor prognosis in gastric cancer patients. AGGF1 can be used as an independent factor to predict postoperative survival of patients with gastric cancer. |Adult [MESH] |Aged [MESH] |Angiogenic Proteins/*biosynthesis [MESH] |Biomarkers, Tumor/*biosynthesis [MESH] |China/epidemiology [MESH] |Female [MESH] |Humans [MESH] |Immunohistochemistry [MESH] |Kaplan-Meier Estimate [MESH] |Male [MESH] |Middle Aged [MESH] |Neovascularization, Pathologic/metabolism [MESH] |Prognosis [MESH] |Proportional Hazards Models [MESH] |Stomach Neoplasms/blood supply/*metabolism/mortality/pathology [MESH] |Survival Rate [MESH]High Expression of Angiogenic Factor with G-Patch and FHA Domain1 (AGG(epmc).pdf DeepDyve Pubget Overpricing