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10.1007/s13317-017-0093-6

http://scihub22266oqcxt.onion/10.1007/s13317-017-0093-6
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C5360668!5360668!28324325
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suck abstract from ncbi


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pmid28324325      Auto+Immun+Highlights 2017 ; 8 (1): ä
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  • The universe of ANA testing: a case for point-of-care ANA testing #MMPMID28324325
  • Konstantinov KN; Rubin RL
  • Auto Immun Highlights 2017[Dec]; 8 (1): ä PMID28324325show ga
  • Testing for total antinuclear antibodies (ANA) is a critical tool for diagnosis and management of autoimmune diseases at both the primary care and subspecialty settings. Repurposing of ANA from a test for lupus to a test for any autoimmune condition has driven the increase in ANA requests. Changes in ANA referral patterns include early or subclinical autoimmune disease detection in patients with low pre-test probability and use of negative ANA results to rule out underlying autoimmune disease. A positive result can lead to further diagnostic considerations. Currently, ANA tests are performed in centralized laboratories; an alternative would be ANA testing at the clinical point-of-care (POC). By virtue of its near real-time data collection capability, low cost, and ease of use, we believe the POC ANA has the potential to enable a new paradigm shift in autoimmune serology testing.
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