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10.3892/ijmm.2017.2859 http://scihub22266oqcxt.onion/10.3892/ijmm.2017.2859 C5360388!5360388!28098880     free     free     free Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Int+J+Mol+Med 2017 ; 39 (3): 498-506 Nephropedia Template TP {{tp|p=28098880|t=2017. The role of gap junctions in inflammatory and neoplastic disorders (Review) |pdf=|usr=}}{{28098880}} gab.com Text The role of gap junctions in inflammatory and neoplastic disorders (Review) JO: Int J Mol Med http://www.kidney.de/pget.php?&tw=1&pmid=28098880 #FOAvip Gap junctions are intercellular channels made of connexin proteins, mediating both electrical and biochemical signals between cells. The ability of gap junction proteins to regulate immune responses, cell proliferation, migration, apoptosis and carcinogenesis makes them attractive therapeutic targets for treating inflammatory and neoplastic disorders in different organ systems. Alterations in gap junction profile and expression levels are observed in hyperproliferative skin disorders, lymphatic vessel diseases, inflammatory lung diseases, liver injury and neoplastic disorders. It is now recognized that the therapeutic effects mediated by traditional pharmacological agents are dependent upon gap junction communication and may even act by influencing gap junction expression or function. Novel strategies for modulating the function or expression of connexins, such as the use of synthetic mimetic peptides and siRNA technology are considered. Twit Text FOAVip The role of gap junctions in inflammatory and neoplastic disorders (Review) ????Int J Mol Med http://www.kidney.de/pget.php?&tw=1&pmid=28098880 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28098880 #FOAvip English Wikipedia <ref>{{Cite pmid|28098880}}</ref> The role of gap junctions in inflammatory and neoplastic disorders (Review) #MMPMID28098880 Wong P; Laxton V; Srivastava S; Chan YWF; Tse G Int J Mol Med 2017[Mar]; 39 (3): 498-506 PMID28098880show ga Gap junctions are intercellular channels made of connexin proteins, mediating both electrical and biochemical signals between cells. The ability of gap junction proteins to regulate immune responses, cell proliferation, migration, apoptosis and carcinogenesis makes them attractive therapeutic targets for treating inflammatory and neoplastic disorders in different organ systems. Alterations in gap junction profile and expression levels are observed in hyperproliferative skin disorders, lymphatic vessel diseases, inflammatory lung diseases, liver injury and neoplastic disorders. It is now recognized that the therapeutic effects mediated by traditional pharmacological agents are dependent upon gap junction communication and may even act by influencing gap junction expression or function. Novel strategies for modulating the function or expression of connexins, such as the use of synthetic mimetic peptides and siRNA technology are considered. äThe role of gap junctions in inflammatory and neoplastic disorders (Re(epmc).pdf DeepDyve Pubget Overpricing