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10.14740/cr330w http://scihub22266oqcxt.onion/10.14740/cr330w C5358175!5358175!28392876     free     free     free Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 211.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 245.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Cardiol+Res 2014 ; 5 (2): 58-67 Nephropedia Template TP {{tp|p=28392876|t=2014. Cardioprotective Effects of Oral Trimetazidine in Diabetic Patients With Anterior Wall Myocardial Infarction Treated with Thrombolysis |pdf=|usr=}}{{28392876}} gab.com Text Cardioprotective Effects of Oral Trimetazidine in Diabetic Patients With Anterior Wall Myocardial Infarction Treated with Thrombolysis JO: Cardiol Res http://www.kidney.de/pget.php?&tw=1&pmid=28392876 #FOAvip Background: Trimetazidine is an anti-ischemic agent with anti-oxidant activity. This study sought to evaluate the impact of oral trimetazidine on extent of myocardial damage in diabetic patients who were presented with anterior wall ST-segment elevation myocardial infarction (STEMI). Methods: One hundred patients were prospectively enrolled, and then randomly assigned to receive oral trimetazidine (70 mg then 35mg bid) (group A, 50 patients) or placebo (group B, 50 patients), starting before thrombolysis. Serum creatine kinase-T and MB (CK-T and CK-MB) were measured serially. Degree of ST-segment resolution was recorded after 90 minutes. Left ventricle ejection fraction (LVEF) was assessed at baseline and after 6 months. Adverse events were recorded after thrombolysis and 6 months later. Results: Mean age of the study cohort was 59.05 ± 3.8 years (males: 60%). After 24 hours, 45 (90%) patients in group A vs. 10 (20%) patients in group B showed peaking of CK-T and CK-MB levels (P < 0.05). Both biomarkers? levels were significantly higher in the placebo group at different sampling times. Complete resolution of ST-segment elevation was recorded in 35 (70%) patients in group A vs. 18 (36%) patients in group B (P < 0.05). Six months later, group A showed higher LVEF and fewer cardiac adverse events (P < 0.05). Conclusion: In diabetic patients receiving thrombolytic therapy for anterior wall STEMI, oral trimetazidine dosing was associated with less myocardial damage, earlier successful reperfusion, improvement of LVEF and less cardiac adverse events. Twit Text FOAVip Cardioprotective Effects of Oral Trimetazidine in Diabetic Patients With Anterior Wall Myocardial Infarction Treated with Thrombolysis ????Cardiol Res http://www.kidney.de/pget.php?&tw=1&pmid=28392876 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28392876 #FOAvip English Wikipedia <ref>{{Cite pmid|28392876}}</ref> Cardioprotective Effects of Oral Trimetazidine in Diabetic Patients With Anterior Wall Myocardial Infarction Treated with Thrombolysis #MMPMID28392876 Shehata M Cardiol Res 2014[Apr]; 5 (2): 58-67 PMID28392876show ga Background: Trimetazidine is an anti-ischemic agent with anti-oxidant activity. This study sought to evaluate the impact of oral trimetazidine on extent of myocardial damage in diabetic patients who were presented with anterior wall ST-segment elevation myocardial infarction (STEMI). Methods: One hundred patients were prospectively enrolled, and then randomly assigned to receive oral trimetazidine (70 mg then 35mg bid) (group A, 50 patients) or placebo (group B, 50 patients), starting before thrombolysis. Serum creatine kinase-T and MB (CK-T and CK-MB) were measured serially. Degree of ST-segment resolution was recorded after 90 minutes. Left ventricle ejection fraction (LVEF) was assessed at baseline and after 6 months. Adverse events were recorded after thrombolysis and 6 months later. Results: Mean age of the study cohort was 59.05 ± 3.8 years (males: 60%). After 24 hours, 45 (90%) patients in group A vs. 10 (20%) patients in group B showed peaking of CK-T and CK-MB levels (P < 0.05). Both biomarkers? levels were significantly higher in the placebo group at different sampling times. Complete resolution of ST-segment elevation was recorded in 35 (70%) patients in group A vs. 18 (36%) patients in group B (P < 0.05). Six months later, group A showed higher LVEF and fewer cardiac adverse events (P < 0.05). Conclusion: In diabetic patients receiving thrombolytic therapy for anterior wall STEMI, oral trimetazidine dosing was associated with less myocardial damage, earlier successful reperfusion, improvement of LVEF and less cardiac adverse events. äCardioprotective Effects of Oral Trimetazidine in Diabetic Patients Wi(epmc).pdf DeepDyve Pubget Overpricing