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10.1155/2017/2925869 http://scihub22266oqcxt.onion/10.1155/2017/2925869 C5357538!5357538!28356914     free     free     free Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Stem+Cells+Int 2017 ; 2017 (ä): ä Nephropedia Template TP {{tp|p=28356914|t=2017. Targeting Signaling Pathways in Cancer Stem Cells for Cancer Treatment |pdf=|usr=}}{{28356914}} gab.com Text Targeting Signaling Pathways in Cancer Stem Cells for Cancer Treatment JO: Stem Cells Int http://www.kidney.de/pget.php?&tw=1&pmid=28356914 #FOAvip The Wnt, Hedgehog, and Notch pathways are inherent signaling pathways in normal embryogenesis, development, and hemostasis. However, dysfunctions of these pathways are evident in multiple tumor types and malignancies. Specifically, aberrant activation of these pathways is implicated in modulation of cancer stem cells (CSCs), a small subset of cancer cells capable of self-renewal and differentiation into heterogeneous tumor cells. The CSCs are accountable for tumor initiation, growth, and recurrence. In this review, we focus on roles of Wnt, Hedgehog, and Notch pathways in CSCs' stemness and functions and summarize therapeutic studies targeting these pathways to eliminate CSCs and improve overall cancer treatment outcomes. Twit Text FOAVip Targeting Signaling Pathways in Cancer Stem Cells for Cancer Treatment ????Stem Cells Int http://www.kidney.de/pget.php?&tw=1&pmid=28356914 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28356914 #FOAvip English Wikipedia <ref>{{Cite pmid|28356914}}</ref> Targeting Signaling Pathways in Cancer Stem Cells for Cancer Treatment #MMPMID28356914 Koury J; Zhong L; Hao J Stem Cells Int 2017[]; 2017 (ä): ä PMID28356914show ga The Wnt, Hedgehog, and Notch pathways are inherent signaling pathways in normal embryogenesis, development, and hemostasis. However, dysfunctions of these pathways are evident in multiple tumor types and malignancies. Specifically, aberrant activation of these pathways is implicated in modulation of cancer stem cells (CSCs), a small subset of cancer cells capable of self-renewal and differentiation into heterogeneous tumor cells. The CSCs are accountable for tumor initiation, growth, and recurrence. In this review, we focus on roles of Wnt, Hedgehog, and Notch pathways in CSCs' stemness and functions and summarize therapeutic studies targeting these pathways to eliminate CSCs and improve overall cancer treatment outcomes. äTargeting Signaling Pathways in Cancer Stem Cells for Cancer Treatment(epmc).pdf DeepDyve Pubget Overpricing