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10.1007/s00535-016-1299-5 http://scihub22266oqcxt.onion/10.1007/s00535-016-1299-5 C5357489!5357489 !28035485     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 243.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\28035485 .jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       J+Gastroenterol 2017 ; 52 (4 ): 419-431 Nephropedia Template TP {{tp|p=28035485 |t=2017. Action and function of Wnt/?-catenin signaling in the progression from chronic hepatitis C to hepatocellular carcinoma |pdf=|usr=}}{{28035485 }} gab.com Text Action and function of Wnt/ -catenin signaling in the progression from chronic hepatitis C to hepatocellular carcinoma JO: J Gastroenterol http://www.kidney.de/pget.php?&tw=1&pmid=28035485 #FOAvip Hepatitis C virus (HCV) infection is one of the leading causes of hepatocellular carcinoma (HCC) worldwide but the mechanistic basis as to how chronic HCV infection furthers the HCC process remains only poorly understood. Accumulating evidence indicates that HCV core and nonstructural proteins provoke activation of the Wnt/?-catenin signaling pathway, and the evidence supporting a role of Wnt/?-catenin signaling in the onset and progression of HCC is compelling. Convincing molecular explanations as to how expression of viral effectors translates into increased activity of the Wnt/?-catenin signaling machinery are still largely lacking, hampering the design of rational strategies aimed at preventing HCC. Furthermore, how such increased signaling is especially associated with HCC oncogenesis in the context of HCV infection remains obscure as well. Here we review the body of contemporary biomedical knowledge on the role of the Wnt/?-catenin pathway in the progression from chronic hepatitis C to cirrhosis and HCC and explore potential hypotheses as to the mechanisms involved. Twit Text FOAVip Action and function of Wnt/ -catenin signaling in the progression from chronic hepatitis C to hepatocellular carcinoma ????J Gastroenterol http://www.kidney.de/pget.php?&tw=1&pmid=28035485 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28035485 #FOAvip English Wikipedia <ref>{{Cite pmid|28035485 }}</ref> Action and function of Wnt/?-catenin signaling in the progression from chronic hepatitis C to hepatocellular carcinoma #MMPMID28035485 Wang W ; Pan Q ; Fuhler GM ; Smits R ; Peppelenbosch MP J Gastroenterol 2017[Apr]; 52 (4 ): 419-431 PMID28035485 show ga Hepatitis C virus (HCV) infection is one of the leading causes of hepatocellular carcinoma (HCC) worldwide but the mechanistic basis as to how chronic HCV infection furthers the HCC process remains only poorly understood. Accumulating evidence indicates that HCV core and nonstructural proteins provoke activation of the Wnt/?-catenin signaling pathway, and the evidence supporting a role of Wnt/?-catenin signaling in the onset and progression of HCC is compelling. Convincing molecular explanations as to how expression of viral effectors translates into increased activity of the Wnt/?-catenin signaling machinery are still largely lacking, hampering the design of rational strategies aimed at preventing HCC. Furthermore, how such increased signaling is especially associated with HCC oncogenesis in the context of HCV infection remains obscure as well. Here we review the body of contemporary biomedical knowledge on the role of the Wnt/?-catenin pathway in the progression from chronic hepatitis C to cirrhosis and HCC and explore potential hypotheses as to the mechanisms involved. |Carcinoma, Hepatocellular/genetics/physiopathology/*virology [MESH] |Cell Transformation, Neoplastic [MESH] |Disease Progression [MESH] |Hepatitis C, Chronic/*complications/physiopathology [MESH] |Humans [MESH] |Liver Cirrhosis/complications/virology [MESH] |Liver Neoplasms/genetics/physiopathology/*virology [MESH] |Mutation [MESH] |Viral Structural Proteins/physiology [MESH] |Wnt Signaling Pathway/genetics/*physiology [MESH]Action and function of Wnt/?-catenin signaling in the progression from(epmc).pdf DeepDyve Pubget Overpricing