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10.18632/oncotarget.12384 http://scihub22266oqcxt.onion/10.18632/oncotarget.12384 C5356689!5356689!27705930     free     free     free Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Oncotarget 2016 ; 7 (51): 84658-65 Nephropedia Template TP {{tp|p=27705930|t=2016. Pyroptosis is involved in the pathogenesis of human hepatocellular carcinoma |pdf=|usr=}}{{27705930}} gab.com Text Pyroptosis is involved in the pathogenesis of human hepatocellular carcinoma JO: Oncotarget http://www.kidney.de/pget.php?&tw=1&pmid=27705930 #FOAvip Pyroptosis is a caspase-1 dependent programmed cell death, which is involved in the pathologic process of several kinds of cancers. Loss of caspase-1 gene expression has been observed in prostate and gastric cancers. However, the role of pyroptosis in human hepatocellular carcinoma (HCC) remains largely unknown. The aim of this study was to investigate the involvement of pyroptosis in the pathogenesis of HCC. Our study showed that pyroptosis was inhibited in HCC tissues and cells. Administration of berberine inhibited the viability, migration and invasion capacity of HepG2 cells through the induction of pyroptosis both in vitro and in vivo, which was attenuated by caspase-1 inhibitor Ac-YVAD-CMK. Conclusively, pyroptosis is involved in the pathogenesis of HCC, and may be a new neoplastic target for the treatment of HCC. Twit Text FOAVip Pyroptosis is involved in the pathogenesis of human hepatocellular carcinoma ????Oncotarget http://www.kidney.de/pget.php?&tw=1&pmid=27705930 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27705930 #FOAvip English Wikipedia <ref>{{Cite pmid|27705930}}</ref> Pyroptosis is involved in the pathogenesis of human hepatocellular carcinoma #MMPMID27705930 Chu Q; Jiang Y; Zhang W; Xu C; Du W; Tuguzbaeva G; Qin Y; Li A; Zhang L; Sun G; Cai Y; Feng Q; Li G; Li Y; Du Z; Bai Y; Yang B Oncotarget 2016[Dec]; 7 (51): 84658-65 PMID27705930show ga Pyroptosis is a caspase-1 dependent programmed cell death, which is involved in the pathologic process of several kinds of cancers. Loss of caspase-1 gene expression has been observed in prostate and gastric cancers. However, the role of pyroptosis in human hepatocellular carcinoma (HCC) remains largely unknown. The aim of this study was to investigate the involvement of pyroptosis in the pathogenesis of HCC. Our study showed that pyroptosis was inhibited in HCC tissues and cells. Administration of berberine inhibited the viability, migration and invasion capacity of HepG2 cells through the induction of pyroptosis both in vitro and in vivo, which was attenuated by caspase-1 inhibitor Ac-YVAD-CMK. Conclusively, pyroptosis is involved in the pathogenesis of HCC, and may be a new neoplastic target for the treatment of HCC. äPyroptosis is involved in the pathogenesis of human hepatocellular car(epmc).pdf DeepDyve Pubget Overpricing