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10.18632/oncotarget.14315 http://scihub22266oqcxt.onion/10.18632/oncotarget.14315 C5355297!5355297!28052019     free     free     free Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 219.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Oncotarget 2017 ; 8 (7): 11708-18 Nephropedia Template TP {{tp|p=28052019|t=2017. TLR-activated plasmacytoid dendritic cells inhibit breast cancer cell growth in vitro and in vivo |pdf=|usr=}}{{28052019}} gab.com Text TLR-activated plasmacytoid dendritic cells inhibit breast cancer cell growth in vitro and in vivo JO: Oncotarget http://www.kidney.de/pget.php?&tw=1&pmid=28052019 #FOAvip Plasmacytoid dendritic cells (pDCs) are a unique subset of naturally occurring dendritic cells, which triggers the production of large amounts of type I interferons (IFNs) after viral infections through Toll-like receptor (TLR) 7 and TLR9. Recent studies have demonstrated that the activation of pDCs kills melanoma cells. However, the role of activated pDCs in breast cancer remains to be determined. In the present study, we generated mouse models of breast cancer and demonstrated that activated pDCs can directly kill breast tumor cells through TRAIL and Granzyme B. Furthermore, we established that pDCs initiate the sequential activation of NK cells and CD8+ T cells, and ultimately inhibit breast tumor growth. Understanding the role of activated pDCs in breast cancer may help to develop new strategies for manipulating the function of pDCs and induce anti-tumor immunity in breast cancer. Twit Text FOAVip TLR-activated plasmacytoid dendritic cells inhibit breast cancer cell growth in vitro and in vivo ????Oncotarget http://www.kidney.de/pget.php?&tw=1&pmid=28052019 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28052019 #FOAvip English Wikipedia <ref>{{Cite pmid|28052019}}</ref> TLR-activated plasmacytoid dendritic cells inhibit breast cancer cell growth in vitro and in vivo #MMPMID28052019 Wu J; Li S; Yang Y; Zhu S; Zhang M; Qiao Y; Liu YJ; Chen J Oncotarget 2017[Feb]; 8 (7): 11708-18 PMID28052019show ga Plasmacytoid dendritic cells (pDCs) are a unique subset of naturally occurring dendritic cells, which triggers the production of large amounts of type I interferons (IFNs) after viral infections through Toll-like receptor (TLR) 7 and TLR9. Recent studies have demonstrated that the activation of pDCs kills melanoma cells. However, the role of activated pDCs in breast cancer remains to be determined. In the present study, we generated mouse models of breast cancer and demonstrated that activated pDCs can directly kill breast tumor cells through TRAIL and Granzyme B. Furthermore, we established that pDCs initiate the sequential activation of NK cells and CD8+ T cells, and ultimately inhibit breast tumor growth. Understanding the role of activated pDCs in breast cancer may help to develop new strategies for manipulating the function of pDCs and induce anti-tumor immunity in breast cancer. äTLR-activated plasmacytoid dendritic cells inhibit breast cancer cell (epmc).pdf DeepDyve Pubget Overpricing