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10.1002/dvdy.24487

http://scihub22266oqcxt.onion/10.1002/dvdy.24487
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C5354960!5354960!28109014
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suck abstract from ncbi


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pmid28109014      Dev+Dyn 2017 ; 246 (4): 336-43
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  • Urothelial Generation and Regeneration in Development, Injury, and Cancer #MMPMID28109014
  • Wang C; Ross WT; Mysorekar IU
  • Dev Dyn 2017[Apr]; 246 (4): 336-43 PMID28109014show ga
  • Homeostatic maintenance and repair of the urothelium upon injury are required for a functional bladder in both healthy and disease conditions. Understanding the cellular and molecular mechanisms underlying the urothelial regenerative response is key to designing strategies for tissue repair and ultimately treatments for urologic diseases including urinary tract infections, voiding dysfunction, painful bladder syndrome and bladder cancer. In this article, we review studies on urothelial ontogeny during development and regeneration following various injury modalities. Signaling pathways involved in urothelial regeneration and in urothelial carcinogenesis are also discussed.
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