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10.1158/0008-5472.CAN-16-2234 http://scihub22266oqcxt.onion/10.1158/0008-5472.CAN-16-2234 C5354959!5354959 !28254862     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=28254862 &cmd=llinks): Failed to open stream: HTTP request failed! 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Advances in the Classification and Treatment of Mastocytosis: Current Status and Outlook toward the Future |pdf=|usr=}}{{28254862 }} gab.com Text Advances in the Classification and Treatment of Mastocytosis: Current Status and Outlook toward the Future JO: Cancer Res http://www.kidney.de/pget.php?&tw=1&pmid=28254862 #FOAvip Mastocytosis is a term used to denote a heterogeneous group of conditions defined by the expansion and accumulation of clonal (neoplastic) tissue mast cells in various organs. The classification of the World Health Organization (WHO) divides the disease into cutaneous mastocytosis, systemic mastocytosis, and localized mast cell tumors. On the basis of histomorphologic criteria, clinical parameters, and organ involvement, systemic mastocytosis is further divided into indolent systemic mastocytosis and advanced systemic mastocytosis variants, including aggressive systemic mastocytosis and mast cell leukemia. The clinical impact and prognostic value of this classification has been confirmed in numerous studies, and its basic concept remains valid. However, refinements have recently been proposed by the consensus group, the WHO, and the European Competence Network on Mastocytosis. In addition, new treatment options are available for patients with advanced systemic mastocytosis, including allogeneic hematopoietic stem cell transplantation and multikinase inhibitors directed against KIT D816V and other key signaling molecules. Our current article provides an overview of recent advances in the field of mastocytosis, with emphasis on classification, prognostication, and emerging new treatment options in advanced systemic mastocytosis. Cancer Res; 77(6); 1261-70. ©2017 AACR. Twit Text FOAVip Advances in the Classification and Treatment of Mastocytosis: Current Status and Outlook toward the Future ????Cancer Res http://www.kidney.de/pget.php?&tw=1&pmid=28254862 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28254862 #FOAvip English Wikipedia <ref>{{Cite pmid|28254862 }}</ref> Advances in the Classification and Treatment of Mastocytosis: Current Status and Outlook toward the Future #MMPMID28254862 Valent P ; Akin C ; Hartmann K ; Nilsson G ; Reiter A ; Hermine O ; Sotlar K ; Sperr WR ; Escribano L ; George TI ; Kluin-Nelemans HC ; Ustun C ; Triggiani M ; Brockow K ; Gotlib J ; Orfao A ; Schwartz LB ; Broesby-Olsen S ; Bindslev-Jensen C ; Kovanen PT ; Galli SJ ; Austen KF ; Arber DA ; Horny HP ; Arock M ; Metcalfe DD Cancer Res 2017[Mar]; 77 (6 ): 1261-1270 PMID28254862 show ga Mastocytosis is a term used to denote a heterogeneous group of conditions defined by the expansion and accumulation of clonal (neoplastic) tissue mast cells in various organs. The classification of the World Health Organization (WHO) divides the disease into cutaneous mastocytosis, systemic mastocytosis, and localized mast cell tumors. On the basis of histomorphologic criteria, clinical parameters, and organ involvement, systemic mastocytosis is further divided into indolent systemic mastocytosis and advanced systemic mastocytosis variants, including aggressive systemic mastocytosis and mast cell leukemia. The clinical impact and prognostic value of this classification has been confirmed in numerous studies, and its basic concept remains valid. However, refinements have recently been proposed by the consensus group, the WHO, and the European Competence Network on Mastocytosis. In addition, new treatment options are available for patients with advanced systemic mastocytosis, including allogeneic hematopoietic stem cell transplantation and multikinase inhibitors directed against KIT D816V and other key signaling molecules. Our current article provides an overview of recent advances in the field of mastocytosis, with emphasis on classification, prognostication, and emerging new treatment options in advanced systemic mastocytosis. Cancer Res; 77(6); 1261-70. ©2017 AACR. |Disease Progression [MESH] |Humans [MESH]Advances in the Classification and Treatment of Mastocytosis: Current (epmc).pdf DeepDyve Pubget Overpricing