Use my Search Websuite to scan PubMed, PMCentral, Journal Hosts and Journal Archives, FullText. Kick-your-searchterm to multiple Engines kick-your-query now !>

A dictionary by aggregated review articles of nephrology, medicine and the life sciences Your one-stop-run pathway from word to the immediate pdf of peer-reviewed on-topic knowledge.

10.18632/oncotarget.13562 http://scihub22266oqcxt.onion/10.18632/oncotarget.13562 C5354935!5354935!27895318     free     free     free Deprecated: Implicit conversion from float 213.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Oncotarget 2017 ; 8 (3): 5629-37 Nephropedia Template TP {{tp|p=27895318|t=2017. Whole genome DNA methylation: beyond genes silencing |pdf=|usr=}}{{27895318}} gab.com Text Whole genome DNA methylation: beyond genes silencing JO: Oncotarget http://www.kidney.de/pget.php?&tw=1&pmid=27895318 #FOAvip The combination of DNA bisulfite treatment with high-throughput sequencing technologies has enabled investigation of genome-wide DNA methylation at near base pair level resolution, far beyond that of the kilobase-long canonical CpG islands that initially revealed the biological relevance of this covalent DNA modification. The latest high-resolution studies have revealed a role for very punctual DNA methylation in chromatin plasticity, gene regulation and splicing. Here, we aim to outline the major biological consequences of DNA methylation recently discovered. We also discuss the necessity of tuning DNA methylation resolution into an adequate scale to ease the integration of the methylome information with other chromatin features and transcription events such as gene expression, nucleosome positioning, transcription factors binding dynamic, gene splicing and genomic imprinting. Finally, our review sheds light on DNA methylation heterogeneity in cell population and the different approaches used for its assessment, including the contribution of single cell DNA analysis technology. Twit Text FOAVip Whole genome DNA methylation: beyond genes silencing ????Oncotarget http://www.kidney.de/pget.php?&tw=1&pmid=27895318 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27895318 #FOAvip English Wikipedia <ref>{{Cite pmid|27895318}}</ref> Whole genome DNA methylation: beyond genes silencing #MMPMID27895318 Tirado-Magallanes R; Rebbani K; Lim R; Pradhan S; Benoukraf T Oncotarget 2017[Jan]; 8 (3): 5629-37 PMID27895318show ga The combination of DNA bisulfite treatment with high-throughput sequencing technologies has enabled investigation of genome-wide DNA methylation at near base pair level resolution, far beyond that of the kilobase-long canonical CpG islands that initially revealed the biological relevance of this covalent DNA modification. The latest high-resolution studies have revealed a role for very punctual DNA methylation in chromatin plasticity, gene regulation and splicing. Here, we aim to outline the major biological consequences of DNA methylation recently discovered. We also discuss the necessity of tuning DNA methylation resolution into an adequate scale to ease the integration of the methylome information with other chromatin features and transcription events such as gene expression, nucleosome positioning, transcription factors binding dynamic, gene splicing and genomic imprinting. Finally, our review sheds light on DNA methylation heterogeneity in cell population and the different approaches used for its assessment, including the contribution of single cell DNA analysis technology. äWhole genome DNA methylation: beyond genes silencing (epmc).pdf DeepDyve Pubget Overpricing