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10.18632/oncotarget.13907 http://scihub22266oqcxt.onion/10.18632/oncotarget.13907 C5354804!5354804!27965469     free     free     free Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Oncotarget 2017 ; 8 (3): 3933-45 Nephropedia Template TP {{tp|p=27965469|t=2017. The role of tumor microenvironment in therapeutic resistance |pdf=|usr=}}{{27965469}} gab.com Text The role of tumor microenvironment in therapeutic resistance JO: Oncotarget http://www.kidney.de/pget.php?&tw=1&pmid=27965469 #FOAvip Cancer cells undergo unlimited progression and survival owing to activation of oncogenes. However, support of the tumor microenvironment is essential to the formation of clinically relevant tumors. Recent evidence indicates that the tumor microenvironment is a critical regulator of immune escape, progression, and distant metastasis of cancer. Moreover, the tumor microenvironment is known to be involved in acquired resistance of tumors to various therapies. Despite significant advances in chemotherapy and radiotherapy, occurrence of therapeutic resistance leads to reduced efficacy. This review highlights myeloid cells, cancer-associated fibroblasts, and mesenchymal stem cells consisting of the tumor microenvironment, as well as the relevant signaling pathways that eventually render cancer cells to be therapeutically resistant. Twit Text FOAVip The role of tumor microenvironment in therapeutic resistance ????Oncotarget http://www.kidney.de/pget.php?&tw=1&pmid=27965469 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27965469 #FOAvip English Wikipedia <ref>{{Cite pmid|27965469}}</ref> The role of tumor microenvironment in therapeutic resistance #MMPMID27965469 Son B; Lee S; Youn H; Kim E; Kim W; Youn B Oncotarget 2017[Jan]; 8 (3): 3933-45 PMID27965469show ga Cancer cells undergo unlimited progression and survival owing to activation of oncogenes. However, support of the tumor microenvironment is essential to the formation of clinically relevant tumors. Recent evidence indicates that the tumor microenvironment is a critical regulator of immune escape, progression, and distant metastasis of cancer. Moreover, the tumor microenvironment is known to be involved in acquired resistance of tumors to various therapies. Despite significant advances in chemotherapy and radiotherapy, occurrence of therapeutic resistance leads to reduced efficacy. This review highlights myeloid cells, cancer-associated fibroblasts, and mesenchymal stem cells consisting of the tumor microenvironment, as well as the relevant signaling pathways that eventually render cancer cells to be therapeutically resistant. äThe role of tumor microenvironment in therapeutic resistance (epmc).pdf DeepDyve Pubget Overpricing