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10.18632/oncotarget.14794 http://scihub22266oqcxt.onion/10.18632/oncotarget.14794 C5354711!5354711!28122334     free     free     free       Oncotarget 2017 ; 8 (6): 9017-20 Nephropedia Template TP {{tp|p=28122334|t=2017. Metformin: a metabolic modulator |pdf=|usr=}}{{28122334}} gab.com Text Metformin: a metabolic modulator JO: Oncotarget http://www.kidney.de/pget.php?&tw=1&pmid=28122334 #FOAvip Recent findings have shed new light on the mechanisms of action through which biguanides exert their anti-aging and cytostatic effects in Caenorhabditis elegans and human cell lines. The drop in energy charge resulting from the metformin mediated inhibition of mitochondrial activity affects the function of the nuclear pore complex, blocks mTOR signaling and enhances the expression of ACAD10. Whether the inhibition of this pathway is truly responsible for the anti-diabetic and cancer effects of the drug in mammals remains to be established. Twit Text FOAVip Metformin: a metabolic modulator ????Oncotarget http://www.kidney.de/pget.php?&tw=1&pmid=28122334 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28122334 #FOAvip English Wikipedia <ref>{{Cite pmid|28122334}}</ref> Metformin: a metabolic modulator #MMPMID28122334 Pietrocola F; Kroemer G Oncotarget 2017[Feb]; 8 (6): 9017-20 PMID28122334show ga Recent findings have shed new light on the mechanisms of action through which biguanides exert their anti-aging and cytostatic effects in Caenorhabditis elegans and human cell lines. The drop in energy charge resulting from the metformin mediated inhibition of mitochondrial activity affects the function of the nuclear pore complex, blocks mTOR signaling and enhances the expression of ACAD10. Whether the inhibition of this pathway is truly responsible for the anti-diabetic and cancer effects of the drug in mammals remains to be established. äMetformin: a metabolic modulator (epmc).pdf DeepDyve Pubget Overpricing