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10.1016/j.devcel.2017.02.003 http://scihub22266oqcxt.onion/10.1016/j.devcel.2017.02.003 C5354100!5354100!28292425     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=28292425&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Dev+Cell 2017 ; 40 (5): 467-477.e5 Nephropedia Template TP {{tp|p=28292425|t=2017. Fat2 and Lar Define a Basally Localized Planar Signaling System Controlling Collective Cell Migration |pdf=|usr=}}{{28292425}} gab.com Text Fat2 and Lar Define a Basally Localized Planar Signaling System Controlling Collective Cell Migration JO: Dev Cell http://www.kidney.de/pget.php?&tw=1&pmid=28292425 #FOAvip Collective migration of epithelial cells underlies diverse tissue remodeling events, but the mechanisms that coordinate individual cell migratory behaviors for collective movement are largely unknown. Studying the Drosophila follicular epithelium, we show that the cadherin Fat2 and the receptor tyrosine phosphatase Lar function in a planar signaling system that coordinates leading and trailing edge dynamics between neighboring cells. Fat2 signals from each cell?s trailing edge to induce leading edge protrusions in the cell behind, in part, by stabilizing Lar?s localization in these cells. Conversely, Lar signals from each cell?s leading edge to stimulate trailing edge retraction in the cell ahead. Fat2/Lar signaling is similar to planar cell polarity signaling in terms of subcellular protein localization; however, Fat2/Lar signaling mediates short-range communication between neighboring cells instead of transmitting long-range information across a tissue. This work defines a key mechanism promoting epithelial migration and establishes a different paradigm for planar cell-cell signaling. Twit Text FOAVip Fat2 and Lar Define a Basally Localized Planar Signaling System Controlling Collective Cell Migration ????Dev Cell http://www.kidney.de/pget.php?&tw=1&pmid=28292425 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28292425 #FOAvip English Wikipedia <ref>{{Cite pmid|28292425}}</ref> Fat2 and Lar Define a Basally Localized Planar Signaling System Controlling Collective Cell Migration #MMPMID28292425 Barlan K; Cetera M; Horne-Badovinac S Dev Cell 2017[Mar]; 40 (5): 467-477.e5 PMID28292425show ga Collective migration of epithelial cells underlies diverse tissue remodeling events, but the mechanisms that coordinate individual cell migratory behaviors for collective movement are largely unknown. Studying the Drosophila follicular epithelium, we show that the cadherin Fat2 and the receptor tyrosine phosphatase Lar function in a planar signaling system that coordinates leading and trailing edge dynamics between neighboring cells. Fat2 signals from each cell?s trailing edge to induce leading edge protrusions in the cell behind, in part, by stabilizing Lar?s localization in these cells. Conversely, Lar signals from each cell?s leading edge to stimulate trailing edge retraction in the cell ahead. Fat2/Lar signaling is similar to planar cell polarity signaling in terms of subcellular protein localization; however, Fat2/Lar signaling mediates short-range communication between neighboring cells instead of transmitting long-range information across a tissue. This work defines a key mechanism promoting epithelial migration and establishes a different paradigm for planar cell-cell signaling. äFat2 and Lar Define a Basally Localized Planar Signaling System Contro(epmc).pdf DeepDyve Pubget Overpricing