Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 251.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 251.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Deprecated: Implicit conversion from float 251.2 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534
Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\27957632
.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 Childs+Nerv+Syst
2017 ; 33
(2
): 297-305
Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Epileptic seizure, as the first symptom of hypoparathyroidism in children, does
not require antiepileptic drugs
#MMPMID27957632
Liu MJ
; Li JW
; Shi XY
; Hu LY
; Zou LP
Childs Nerv Syst
2017[Feb]; 33
(2
): 297-305
PMID27957632
show ga
OBJECTIVE: Patients with hypoparathyroidism exhibit metabolic disorders
(hypocalcemia) and brain structural abnormalities (brain calcifications).
Currently, studies have determined whether antiepileptic drug (AED) treatment is
required for epileptic seizures in children with hypoparathyroidism. METHOD: This
study aims to evaluate the data of two medical centers in Beijing based on the
diagnosis of epileptic seizures as the first symptom of hypoparathyroidism in
children. RESULT: A total of 42 patients were included and assigned into AED and
non-AED treatment groups in a 1:2 matched case-control study. Results show that
the seizure outcome after 1 year of AED treatment is not significantly different
from that of the control. In the subgroup analysis of patients with subcortical
calcifications, the seizure outcome is still not significantly different from
that of the control. CONCLUSION: Thus, AED treatment cannot improve the seizure
outcomes in children with parathyroid disorder, even in such cases as suspected
structural seizure caused by subcortical calcifications. Clinicians must take
adequate considerations on the use of AEDs in these patients. Epileptic seizures,
as the first symptom of hypoparathyroidism in children, do not require epilepsy
drugs.