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10.14814/phy2.13190 http://scihub22266oqcxt.onion/10.14814/phy2.13190 C5350187!5350187!28292878     free     free     free Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 229.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Warning: imagejpeg(C:\Inetpub\vhosts\kidney.de\httpdocs\phplern\28292878.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117       Physiol+Rep 2017 ; 5 (5): ä Nephropedia Template TP {{tp|p=28292878|t=2017. Pneumonia treatment by photodynamic therapy with extracorporeal illumination ? an experimental model |pdf=|usr=}}{{28292878}} gab.com Text Pneumonia treatment by photodynamic therapy with extracorporeal illumination an experimental model JO: Physiol Rep http://www.kidney.de/pget.php?&tw=1&pmid=28292878 #FOAvip Infectious pneumonia is a major cause of morbidity/mortality, mainly because of the increasing rate of microorganisms resistant to antibiotics. Photodynamic Therapy (PDT) is emerging as a promising approach, as effects are based on oxidative stress, preventing microorganism resistance. In two previous studies, the in vitro inactivation of Streptococcus pneumoniae using indocyanine green (ICG) and infrared light source was a success killing 5 log10 colony?forming units (CFU/mL) with only 10 ?mol/L ICG. In this work, a proof?of?principle protocol was designed to treat lung infections by PDT using extracorporeal illumination with a 780 nm laser device and also ICG as photosensitizer. Hairless mice were infected with S. pneumoniae and PDT was performed two days after infection. For control groups, CFU recovery ranged between 103?104/mouse. For PDT group, however, no bacteria were recovered in 80% of the animals. Based on this result, animal survival was evaluated separately over 50 days. No deaths occurred in PDT group, whereas 60% of the control group died. Our results indicate that extracorporeal PDT has the potential for pneumonia treatment, and pulmonary decontamination with PDT may be used as a single therapy or as an antibiotics adjuvant. Twit Text FOAVip Pneumonia treatment by photodynamic therapy with extracorporeal illumination an experimental model ????Physiol Rep http://www.kidney.de/pget.php?&tw=1&pmid=28292878 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28292878 #FOAvip English Wikipedia <ref>{{Cite pmid|28292878}}</ref> Pneumonia treatment by photodynamic therapy with extracorporeal illumination ? an experimental model #MMPMID28292878 Geralde MC; Leite IS; Inada NM; Salina ACG; Medeiros AI; Kuebler WM; Kurachi C; Bagnato VS Physiol Rep 2017[Mar]; 5 (5): ä PMID28292878show ga Infectious pneumonia is a major cause of morbidity/mortality, mainly because of the increasing rate of microorganisms resistant to antibiotics. Photodynamic Therapy (PDT) is emerging as a promising approach, as effects are based on oxidative stress, preventing microorganism resistance. In two previous studies, the in vitro inactivation of Streptococcus pneumoniae using indocyanine green (ICG) and infrared light source was a success killing 5 log10 colony?forming units (CFU/mL) with only 10 ?mol/L ICG. In this work, a proof?of?principle protocol was designed to treat lung infections by PDT using extracorporeal illumination with a 780 nm laser device and also ICG as photosensitizer. Hairless mice were infected with S. pneumoniae and PDT was performed two days after infection. For control groups, CFU recovery ranged between 103?104/mouse. For PDT group, however, no bacteria were recovered in 80% of the animals. Based on this result, animal survival was evaluated separately over 50 days. No deaths occurred in PDT group, whereas 60% of the control group died. Our results indicate that extracorporeal PDT has the potential for pneumonia treatment, and pulmonary decontamination with PDT may be used as a single therapy or as an antibiotics adjuvant. äPneumonia treatment by photodynamic therapy with extracorporeal illumi(epmc).pdf DeepDyve Pubget Overpricing