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10.1091/mbc.E16-07-0517

http://scihub22266oqcxt.onion/10.1091/mbc.E16-07-0517
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C5349777!5349777!28292915
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suck abstract from ncbi


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pmid28292915      Mol+Biol+Cell 2017 ; 28 (6): 707-11
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  • A cascade of multiple proteins and lipids catalyzes membrane fusion #MMPMID28292915
  • Wickner W; Rizo J
  • Mol Biol Cell 2017[Mar]; 28 (6): 707-11 PMID28292915show ga
  • Recent studies suggest revisions to the SNARE paradigm of membrane fusion. Membrane tethers and/or SNAREs recruit proteins of the Sec 1/Munc18 family to catalyze SNARE assembly into trans-complexes. SNARE-domain zippering draws the bilayers into immediate apposition and provides a platform to position fusion triggers such as Sec 17/?-SNAP and/or synaptotagmin, which insert their apolar ?wedge? domains into the bilayers, initiating the lipid rearrangements of fusion.
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