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10.2169/internalmedicine.56.6856

http://scihub22266oqcxt.onion/10.2169/internalmedicine.56.6856
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C5348460!5348460 !28154280
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suck abstract from ncbi

pmid28154280
      Intern+Med 2017 ; 56 (3 ): 341-346
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  • An Atypical Clinical Course of Anti-MDA5 Antibody-positive Interstitial Lung Disease in a Patient with Three Deteriorations in 9 years #MMPMID28154280
  • Sato Y ; Otsuka K ; Tamai K ; Ono Y ; Hamaguchi Y ; Tomii K
  • Intern Med 2017[]; 56 (3 ): 341-346 PMID28154280 show ga
  • Anti-MDA5 antibody-positive patients with clinically amyopathic dermatomyositis (CADM) are at high risk of developing rapidly progressive interstitial lung disease (ILD), which is associated with a high mortality rate. Approximately half of the patients with ILD recover; however, the long-term clinical course of these patients has not been fully reported and is not completely understood. This report describes the atypical clinical course of an anti-MDA5 antibody-positive CADM patient who experienced three deteriorations of ILD in 9 years. These findings indicate that the ILD in anti-MDA5 antibody-positive patients may not only be rapidly progressive, but may also be chronic and recurrent.
  • |Antibodies, Anti-Idiotypic/*immunology [MESH]
  • |DEAD-box RNA Helicases/immunology [MESH]
  • |Dermatomyositis/complications/*immunology [MESH]
  • |Humans [MESH]
  • |Intercellular Signaling Peptides and Proteins [MESH]
  • |Interferon-Induced Helicase, IFIH1/immunology [MESH]
  • |Lung Diseases, Interstitial/complications/diagnosis/*immunology [MESH]
  • |Male [MESH]
  • |Middle Aged [MESH]


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