Topical Atropine in the Control of Myopia #MMPMID28293653
GALVIS V; TELLO A; PARRA MM; MERAYO-LLOVES J; LARREA J; JULIAN RODRIGUEZ C; CAMACHO PA
Med Hypothesis Discov Innov Ophthalmol 2016[Aut]; 5 (3): 78-88 PMID28293653show ga
Atropine has been used for more than a century to arrest myopia progression. Compelling evidence of its protective effect has been reported in well-designed clinical studies, mainly performed during the last two decades. However, its exact mechanism of action has not been determined. Experimental findings have shown that the mechanism is not related to accommodation, as was thought for decades. A review of the published literature revealed a significant amount of evidence supporting its safety and efficacy at a concentration of 1.0%, and at lower concentrations (as low as 0.01%).