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10.1111/jcmm.13008 http://scihub22266oqcxt.onion/10.1111/jcmm.13008 C5345622!5345622!27860262     free     free     free Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 215.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Cell+Mol+Med 2017 ; 21 (4): 648-57 Nephropedia Template TP {{tp|p=27860262|t=2017. Ferroptosis, a new form of cell death, and its relationships with tumourous diseases |pdf=|usr=}}{{27860262}} gab.com Text Ferroptosis, a new form of cell death, and its relationships with tumourous diseases JO: J Cell Mol Med http://www.kidney.de/pget.php?&tw=1&pmid=27860262 #FOAvip Ferroptosis is a newly discovered type of cell death that differs from traditional apoptosis and necrosis and results from iron?dependent lipid peroxide accumulation. Ferroptotic cell death is characterized by cytological changes, including cell volume shrinkage and increased mitochondrial membrane density. Ferroptosis can be induced by two classes of small?molecule substances known as class 1 (system Xc? inhibitors) and class 2 ferroptosis inducers [glutathione peroxidase 4 (GPx4) inhibitors]. In addition to these small?molecule substances, a number of drugs (e.g. sorafenib, artemisinin and its derivatives) can induce ferroptosis. Various factors, such as the mevalonate (MVA) and sulphur?transfer pathways, play pivotal roles in the regulation of ferroptosis. Ferroptosis plays an unneglectable role in regulating the growth and proliferation of some types of tumour cells, such as lymphocytoma, ductal cell cancer of the pancreas, renal cell carcinoma (RCC) and hepatocellular carcinoma (HCC). Here, we will first introduce the discovery of and research pertaining to ferroptosis; then summarize the induction mechanisms and regulatory pathways of ferroptosis; and finally, further elucidate the roles of ferroptosis in human tumourous diseases. Twit Text FOAVip Ferroptosis, a new form of cell death, and its relationships with tumourous diseases ????J Cell Mol Med http://www.kidney.de/pget.php?&tw=1&pmid=27860262 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27860262 #FOAvip English Wikipedia <ref>{{Cite pmid|27860262}}</ref> Ferroptosis, a new form of cell death, and its relationships with tumourous diseases #MMPMID27860262 Yu H; Guo P; Xie X; Wang Y; Chen G J Cell Mol Med 2017[Apr]; 21 (4): 648-57 PMID27860262show ga Ferroptosis is a newly discovered type of cell death that differs from traditional apoptosis and necrosis and results from iron?dependent lipid peroxide accumulation. Ferroptotic cell death is characterized by cytological changes, including cell volume shrinkage and increased mitochondrial membrane density. Ferroptosis can be induced by two classes of small?molecule substances known as class 1 (system Xc? inhibitors) and class 2 ferroptosis inducers [glutathione peroxidase 4 (GPx4) inhibitors]. In addition to these small?molecule substances, a number of drugs (e.g. sorafenib, artemisinin and its derivatives) can induce ferroptosis. Various factors, such as the mevalonate (MVA) and sulphur?transfer pathways, play pivotal roles in the regulation of ferroptosis. Ferroptosis plays an unneglectable role in regulating the growth and proliferation of some types of tumour cells, such as lymphocytoma, ductal cell cancer of the pancreas, renal cell carcinoma (RCC) and hepatocellular carcinoma (HCC). Here, we will first introduce the discovery of and research pertaining to ferroptosis; then summarize the induction mechanisms and regulatory pathways of ferroptosis; and finally, further elucidate the roles of ferroptosis in human tumourous diseases. äFerroptosis, a new form of cell death, and its relationships with tumo(epmc).pdf DeepDyve Pubget Overpricing