Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=27476791
&cmd=llinks): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests
in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 215
Innate and adaptive immunologic functions of complement in the host response to
Listeria monocytogenes infection
#MMPMID27476791
Calame DG
; Mueller-Ortiz SL
; Wetsel RA
Immunobiology
2016[Dec]; 221
(12
): 1407-1417
PMID27476791
show ga
Listeria monocytogenes is a leading cause of foodborne-illness associated
mortality that has attracted considerable attention in recent years due to
several significant outbreaks. It has also served as a model organism for the
study of intracellular pathogens. For these reasons the host response to L.
monocytogenes has long been the subject of investigation. A potent innate and
adaptive immune response is required for containment and clearance of L.
monocytogenes. However, some elements of this response, such as type 1
interferons, can be detrimental to the host. Recent studies have revealed novel
functions for the complement system, an ancient arm of innate immunity, in this
process. Here we review the role of complement in the host response to L.
monocytogenes.