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.jpg): Failed to open stream: No such file or directory in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 117 J+Kidney+Cancer+VHL
2015 ; 2
(3
): 134-139
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Collecting Duct Renal Cell Carcinoma Found to Involve the Collecting System
During Partial Nephrectomy: A Case Report
#MMPMID28326268
Harbin AC
; Styskel BA
; Patel V
; Wang H
; Eun DD
J Kidney Cancer VHL
2015[]; 2
(3
): 134-139
PMID28326268
show ga
Collecting duct carcinoma (CDC) is a rare and aggressive form of renal cell
carcinoma (RCC) arising from the principal cells of the collecting duct. One
third of cases present with metastatic disease, but many present in a manner
similar to conventional RCC or urothelial carcinoma (UC). We discuss a case of
CDC which presented as a small mass at the cortico-medullary junction, and was
discovered at robotic partial nephrectomy (RPN) to be grossly involving the
collecting system. A 62-year-old man presented with a small renal mass suspicious
for RCC, which was found on computed tomography (CT) after an episode of gross
hematuria. After thorough workup, RPN was attempted; however, intraoperatively
the mass was found to be involving the collecting system. Radical
nephroureterectomy was performed, and the pathology report revealed CDC. CDC is a
rare and aggressive form of RCC. While many cases are metastatic at diagnosis,
most patients present with the incidental finding of a small renal mass. There
are no reports of a CDC involving the collecting system at RPN after negative
ureteroscopy preoperatively. The adjuvant therapeutic options for CDC are
limited, and long term survival is poor.