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2017 ; 11
(1
): 50-52
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Snake in the grass: A case report of transfusion reactions due to contaminated
donor arm disinfectant
#MMPMID28316441
Dubey A
; Sonker A
; Chaudhary R
Asian J Transfus Sci
2017[Jan]; 11
(1
): 50-52
PMID28316441
show ga
Bacterial contamination of blood components remains an on-going challenge. In the
majority of cases, organisms contaminating the blood components are a part of
normal skin flora. Here, we report a case of bacterial contamination of blood
units through contaminated donor arm disinfectant. There was a series of
reactions due to random donor platelet (RDP) transfusion. The patients had
features of septic transfusion reactions. On root cause analysis, spirit swabs
used for disinfection of donors' arm were identified as the culprit and presence
of Clostridium difficile was established. All the blood components prepared on
the dates of implicated RDP units were removed from the stock and we replaced the
existing 70% alcohol disinfectant with chlorhexidine-alcohol-based antiseptic
rub. Further, no such transfusion reactions were reported. Implementation of good
donor arm disinfection technique in addition to the use of blood bags with
diversion pouch is proposed to be best preventive strategy for resource-poor
settings.