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2017 ; 11
(ä): 575-583
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Human papillomavirus (HPV): systemic treatment with Gene-Eden-VIR/Novirin safely
and effectively clears virus
#MMPMID28424535
Polansky H
; Itzkovitz E
; Javaherian A
Drug Des Devel Ther
2017[]; 11
(ä): 575-583
PMID28424535
show ga
PURPOSE: This paper reports the results of a clinical study that tested the
effect of systemic treatment with the botanical product Gene-Eden-VIR/Novirin on
the clearance rate (also called time to clearance) of the human papillomavirus
(HPV). The study compared the clearance rate in treated and untreated individuals
suffering from a symptomatic HPV infection. The data on the untreated individuals
were obtained by reverse engineering of the Kaplan-Meier figures in five
published papers. MATERIALS AND METHODS: The study included 59 treated
participants. All participants were suffering from a symptomatic HPV infection
prior to the commencement of treatment. The treatment was one to four capsules of
Gene-Eden-VIR/Novirin per day. The duration of treatment was 2-12 months. The
study included five groups of external controls with diverse characteristics.
RESULTS: The mean time to clearance in Gene-Eden-VIR/Novirin-treated individuals
was 5.1 months or 151.5 days (95% CI: 4.2-5.9 months or 95% CI: 125.7-177.3 days,
respectively). The median time to clearance was 3.5 months. The mean time to
clearance in the five untreated groups ranged from 6.9 to 20.0 months (P<0.0001
for the difference between treatment group and each untreated group). Also, 100%
of the participants in the treatment group were HPV free at the end of 12 months
vs 53%, 52%, 65%, 20%, and 77% in the untreated control groups. The treated
participants reported no adverse experiences. CONCLUSION: This clinical study has
two major contributions. First, it showed that systemic treatment with the
natural Gene-Eden-VIR/Novirin decreased the time to HPV clearance, increased the
percentage of HPV-free individuals, and caused no adverse experiences in
individuals suffering from a symptomatic HPV infection. Since there are no other
systemic treatments for symptomatic HPV infections, this study presents highly
valuable information on the clinical effects of the first treatment in this
category. Second, the study presents a new method for conducting clinical studies
that addresses one of the major deficiencies associated with the practice of the
randomized controlled trial method.
free
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