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2017 ; 12
(3
): e0171670
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Sickness behavior in feverish children is independent of the severity of fever
An observational, multicenter study
#MMPMID28278190
Corrard F
; Copin C
; Wollner A
; Elbez A
; Derkx V
; Bechet S
; Levy C
; Boucherat M
; Cohen R
PLoS One
2017[]; 12
(3
): e0171670
PMID28278190
show ga
BACKGROUND. OBJECTIVES: Behavioral changes in a febrile child are usually
considered to stem from the fever. We studied sickness behavior (SB) in terms of
its clinical components and its relation to fever. METHODS: This observational,
multicenter study included children aged 6 months to 3 years who were either
febrile (fever ?12 hours, ? 39°C and ?38°C at inclusion) or non-febrile and well.
The child had to have been awake for the 2 hours preceding the consultation and
cared for by the parent who brought him/her to the doctor. SB was evaluated
according to 6 parameters over this 2-hour period: time spent playing, distance
covered, time spent seeking comfort, time spent whining or crying, time spent in
a state of irritation or of anger, most distorted facial expression. Two
parameters were assessed for the 24-hour period preceding the consultation: time
spent sleeping and appetite. The parent reported the degree of change in these
parameters compared with the usual situation, using rating scales. RESULTS: 200
febrile children (most with nonspecific upper respiratory infections) and 200
non-febrile children were included. The mean values of the 8 parameters differed
significantly (p<0.001) between the 2 groups and were independent of the height
of fever at inclusion in the febrile children. In the study conditions,
paracetamol failed to improve SB when the child was still feverish. CONCLUSION:
The 8 parameters suggested that SB and fever are two independent manifestations
that are activated simultaneously during an infection. This independence is in
harmony with recommendations to treat the discomfort of SB and not the fever.
|*Illness Behavior
[MESH]
|*Severity of Illness Index
[MESH]
|Anti-Inflammatory Agents, Non-Steroidal/therapeutic use
[MESH]