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10.3390/ijms18020450 http://scihub22266oqcxt.onion/10.3390/ijms18020450 C5343984!5343984 !28230721     free     free     free Warning: file_get_contents(https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&id=28230721 &cmd=llinks): Failed to open stream: HTTP request failed! 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The Interplay of LncRNA-H19 and Its Binding Partners in Physiological Process and Gastric Carcinogenesis |pdf=|usr=}}{{28230721 }} gab.com Text The Interplay of LncRNA-H19 and Its Binding Partners in Physiological Process and Gastric Carcinogenesis JO: Int J Mol Sci http://www.kidney.de/pget.php?&tw=1&pmid=28230721 #FOAvip Long non-coding RNA (lncRNA), a novel and effective modulator in carcinogenesis, has become a study hotspot in recent years. The imprinted oncofetal lncRNA H19 is one of the first identified imprinted lncRNAs with a high expression level in embryogenesis but is barely detectable in most tissues after birth. Aberrant alterations of H19 expression have been demonstrated in various tumors, including gastric cancer (GC), implicating a crucial role of H19 in cancer progression. As one of the top malignancies in the world, GC has already become a serious concern to public health with poor prognosis. The regulatory roles of H19 in gastric carcinogenesis have been explored by various research groups, which leads to the development of GC therapy. This review comprehensively summarizes the current knowledge of H19 in tumorigenesis, especially in GC pathogenesis, with emphasis on the underneath molecular mechanisms depicted from its functional partners. Furthermore, the accumulated knowledge of H19 will provide better understanding on targeted therapy of GC. Twit Text FOAVip The Interplay of LncRNA-H19 and Its Binding Partners in Physiological Process and Gastric Carcinogenesis ????Int J Mol Sci http://www.kidney.de/pget.php?&tw=1&pmid=28230721 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28230721 #FOAvip English Wikipedia <ref>{{Cite pmid|28230721 }}</ref> The Interplay of LncRNA-H19 and Its Binding Partners in Physiological Process and Gastric Carcinogenesis #MMPMID28230721 Zhang L ; Zhou Y ; Huang T ; Cheng AS ; Yu J ; Kang W ; To KF Int J Mol Sci 2017[Feb]; 18 (2 ): ä PMID28230721 show ga Long non-coding RNA (lncRNA), a novel and effective modulator in carcinogenesis, has become a study hotspot in recent years. The imprinted oncofetal lncRNA H19 is one of the first identified imprinted lncRNAs with a high expression level in embryogenesis but is barely detectable in most tissues after birth. Aberrant alterations of H19 expression have been demonstrated in various tumors, including gastric cancer (GC), implicating a crucial role of H19 in cancer progression. As one of the top malignancies in the world, GC has already become a serious concern to public health with poor prognosis. The regulatory roles of H19 in gastric carcinogenesis have been explored by various research groups, which leads to the development of GC therapy. This review comprehensively summarizes the current knowledge of H19 in tumorigenesis, especially in GC pathogenesis, with emphasis on the underneath molecular mechanisms depicted from its functional partners. Furthermore, the accumulated knowledge of H19 will provide better understanding on targeted therapy of GC. |Animals [MESH] |Carcinogenesis/*genetics/metabolism [MESH] |DNA Methylation [MESH] |Gene Expression Regulation [MESH] |Gene Expression Regulation, Neoplastic [MESH] |Humans [MESH] |MicroRNAs/genetics/metabolism [MESH] |RNA, Long Noncoding/*genetics/metabolism [MESH] |RNA-Binding Proteins/metabolism [MESH]The Interplay of LncRNA-H19 and Its Binding Partners in Physiological (epmc).pdf DeepDyve Pubget Overpricing