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2017 ; 18
(2
): ä Nephropedia Template TP
gab.com Text
Twit Text FOAVip
Twit Text #
English Wikipedia
Radiation-Induced Organizing Pneumonia: A Characteristic Disease that Requires
Symptom-Oriented Management
#MMPMID28134830
Otani K
; Seo Y
; Ogawa K
Int J Mol Sci
2017[Jan]; 18
(2
): ä PMID28134830
show ga
Radiation-induced organizing pneumonia (RIOP) is an inflammatory lung disease
that is occasionally observed after irradiation to the breast. It is a type of
secondary organizing pneumonia that is characterized by infiltrates outside the
irradiated volume that are sometimes migratory. Corticosteroids work acutely, but
relapse of pneumonia is often experienced. Management of RIOP should simply be
symptom-oriented, and the use of corticosteroids should be limited to severe
symptoms from the perspective not only of cost-effectiveness but also of cancer
treatment. Once steroid therapy is started, it takes a long time to stop it due
to frequent relapses. We review RIOP from the perspective of its diagnosis,
epidemiology, molecular pathogenesis, and patient management.