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2017 ; 6
(ä): 10
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Cornea Collagen Cross-linking for Keratoconus: A Comparison between Accelerated
and Conventional Methods
#MMPMID28299302
Razmjoo H
; Peyman A
; Rahimi A
; Modrek HJ
Adv Biomed Res
2017[]; 6
(ä): 10
PMID28299302
show ga
BACKGROUND: Keratoconus is a progressive degenerative disorder of the cornea in
which structural changes in the cornea cause it to become thin and conical in
shape. Recently, collagen cross-linking (CXL) has been introduced as an effective
intervention in management of progressive keratoconus. Accelerated CXL is a new
protocol of this procedure which reduces corneal ultraviolet irradiation exposure
time to 5 min. This study aimed to compare visual acuity, keratometry and
topographic criteria of keratoconic eyes after conventional and accelerated CXL
with a six-month follow-up. MATERIALS AND METHODS: In this prospective
interventional study we assessed eyes of 40 patients. Patients were divided into
two groups randomly. One group underwent accelerated (5 min) CXL and the other
underwent conventional (30 min) CXL. Visual acuity, topographic criteria and
keratometry were assessed preoperatively and 6 months postoperatively. RESULTS:
In the present study we assessed 40 patients, 50% of which were right eye (OD)
and 50% were left eye (OS). Mean age of patients in the accelerated group was
22.10 and in the conventional group was 22.80 years. Our results showed no
significant differences between visual acuity, keratometric and topographic
criteria in the two groups before intervention. Likewise our results manifested
no significant difference between visual acuity, keratometric, refractive and
topographic criteria after intervention. CONCLUSION: According to our survey
topographic criteria and keratometry improvement in the accelerated and
conventional protocol are the same. So accelerated protocol is suggested as a
safe and effective option for management of progressive keratoconus.