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10.1186/s12886-017-0412-8 http://scihub22266oqcxt.onion/10.1186/s12886-017-0412-8 C5341407!5341407!28270126     free     free     free Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 233.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       BMC+Ophthalmol 2017 ; 17 (ä): ä Nephropedia Template TP {{tp|p=28270126|t=2017. Analysis of novel Sjogren?s syndrome autoantibodies in patients with dry eyes |pdf=|usr=}}{{28270126}} gab.com Text Analysis of novel Sjogren s syndrome autoantibodies in patients with dry eyes JO: BMC Ophthalmol http://www.kidney.de/pget.php?&tw=1&pmid=28270126 #FOAvip Background: Dry eye is a common problem in Ophthalmology and may occur for many reasons including Sjogren?s syndrome (SS). Recent studies have identified autoantibodies, anti-salivary gland protein 1 (SP1), anti-carbonic anhydrase 6 (CA6) and anti-parotid secretory protein (PSP), which occur early in the course of SS.The current studies were designed to evaluate how many patients with idiopathic dry eye and no evidence of systemic diseases from a dry eye practice have these autoantibodies. Methods: Patients from a dry eye clinic and normal controls were assessed by Schirmer?s test for tear flow. Sera were assessed for autoantibodies using ELISA assays. Statistics was performed with Prism 7 software and student?s unpaired t test. Results: In this study 60% of the dry eye patients expressed one of these autoantibodies. Only 30% expressed one of the autoantibodies associated with long-standing SS, which are included in the diagnostic criteria for SS, anti-Ro and anti-La. Patients with disease for less than 2 years and mild dry eyes did not express anti-Ro or anti-La, while 25% expressed anti-SP1. Similar observations, with smaller numbers, were made when patients had not only dry eye but also dry mouth. Conclusions: Antibodies to SP1, CA6 and PSP occur in some patients with idiopathic dry eyes. Further studies will be needed to determine how many of these patients go on to develop systemic manifestations of SS. Testing for these autoantibodies may allow early recognition of patients with SS. This will lead to improved management of the patients and the development of new strategies to maintain normal lacrimal and salivary gland function in patients with SS. Twit Text FOAVip Analysis of novel Sjogren s syndrome autoantibodies in patients with dry eyes ????BMC Ophthalmol http://www.kidney.de/pget.php?&tw=1&pmid=28270126 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28270126 #FOAvip English Wikipedia <ref>{{Cite pmid|28270126}}</ref> Analysis of novel Sjogren?s syndrome autoantibodies in patients with dry eyes #MMPMID28270126 Everett S; Vishwanath S; Cavero V; Shen L; Suresh L; Malyavantham K; Lincoff-Cohen N; Ambrus JL BMC Ophthalmol 2017[]; 17 (ä): ä PMID28270126show ga Background: Dry eye is a common problem in Ophthalmology and may occur for many reasons including Sjogren?s syndrome (SS). Recent studies have identified autoantibodies, anti-salivary gland protein 1 (SP1), anti-carbonic anhydrase 6 (CA6) and anti-parotid secretory protein (PSP), which occur early in the course of SS.The current studies were designed to evaluate how many patients with idiopathic dry eye and no evidence of systemic diseases from a dry eye practice have these autoantibodies. Methods: Patients from a dry eye clinic and normal controls were assessed by Schirmer?s test for tear flow. Sera were assessed for autoantibodies using ELISA assays. Statistics was performed with Prism 7 software and student?s unpaired t test. Results: In this study 60% of the dry eye patients expressed one of these autoantibodies. Only 30% expressed one of the autoantibodies associated with long-standing SS, which are included in the diagnostic criteria for SS, anti-Ro and anti-La. Patients with disease for less than 2 years and mild dry eyes did not express anti-Ro or anti-La, while 25% expressed anti-SP1. Similar observations, with smaller numbers, were made when patients had not only dry eye but also dry mouth. Conclusions: Antibodies to SP1, CA6 and PSP occur in some patients with idiopathic dry eyes. Further studies will be needed to determine how many of these patients go on to develop systemic manifestations of SS. Testing for these autoantibodies may allow early recognition of patients with SS. This will lead to improved management of the patients and the development of new strategies to maintain normal lacrimal and salivary gland function in patients with SS. äAnalysis of novel Sjogren?s syndrome autoantibodies in patients with d(epmc).pdf DeepDyve Pubget Overpricing