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2017 ; 96
(9
): e5822
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Acute kidney injury in patients with pulmonary embolism: A population-based
cohort study
#MMPMID28248851
Chang CH
; Fu CM
; Fan PC
; Chen SW
; Chang SW
; Mao CT
; Tian YC
; Chen YC
; Chu PH
; Chen TH
Medicine (Baltimore)
2017[Mar]; 96
(9
): e5822
PMID28248851
show ga
Acute kidney injury (AKI) is overlooked in patients with pulmonary embolism (PE).
Risk factors for and long-term outcomes of this complication remain unknown. This
study evaluated the predictors and prognosis of AKI in patients with PE.This
retrospective cohort study used Taiwan's National Health Insurance Research
Database. We enrolled a total of 7588 patients who were admitted to a hospital
for PE from January1997 to December 2011 and administered anticoagulation or
thrombolytic agents. All demographic data, risk factors, and outcomes were
analyzed.AKI was diagnosed in 372 (4.9%) patients. Multivariate logistic
regression analysis revealed pre-existing chronic kidney disease, hypertension,
diabetes mellitus, massive PE, anemia, and sepsis as independent risk factors for
AKI. In the long-term follow-up, the survival rate was similar in the AKI and
non-AKI groups.Careful risk factor screening and intensive intervention in
patients with AKI might yield outcomes similar to those in patients without AKI.