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10.2147/JAA.S129160

http://scihub22266oqcxt.onion/10.2147/JAA.S129160
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C5338956!5338956!28280372
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suck abstract from ncbi

pmid28280372      J+Asthma+Allergy 2017 ; 10 (ä): 31-3
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  • Pediatric anaphylaxis and hyper IgE syndrome #MMPMID28280372
  • Dosanjh A
  • J Asthma Allergy 2017[]; 10 (ä): 31-3 PMID28280372show ga
  • Patients with autosomal-dominant (AD) hyper immunoglobulin E (IgE) syndrome (HIES) or Job syndrome develop frequent dermatologic and pulmonary infections. As patients have an extreme elevation of IgE levels, this database analysis study sought to study the association between AD HIES, Job syndrome, and anaphylaxis. HIES is a heterogeneous group of immune disorders characterized by extremely elevated levels of serum IgE. Although the molecular defects and clinical phenotypes found in association with Job syndrome are well characterized, the association with severe allergic reactions and anaphylaxis is a subject of ongoing investigation.
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