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10.1387/ijdb.160274id

http://scihub22266oqcxt.onion/10.1387/ijdb.160274id
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C5338735!5338735!28000905
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suck abstract from ncbi


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pmid28000905      Int+J+Dev+Biol 2016 ; 60 (10-11-12): 337-419
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  • Teratomas produced from human pluripotent stem cells xenografted into immunodeficient mice - a histopathology atlas #MMPMID28000905
  • Damjanov I; Andrews PW
  • Int J Dev Biol 2016[]; 60 (10-11-12): 337-419 PMID28000905show ga
  • This atlas illustrates the microscopic features of tumors produced from human pluripotent stem cells (hPSCs) xenografted into immunosuppressed mice, according to the generally accepted protocols for performing this teratoma assay of stem cell pluripotency. Microphotographs depict various hematoxylin and eosin (H&E) stained tissues derived from all three embryonic germ layers (ectoderm, mesoderm and endoderm). The appearance of persistent hPSC in teratomas is also described with special emphasis on the morphogenesis of embryoid bodies and yolk sac components surrounding them. The use of immunohistochemistry for analyzing hPSC-derived teratomas is also illustrated.
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