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10.1038/srep43426 http://scihub22266oqcxt.onion/10.1038/srep43426 C5338274!5338274!28262704     free     free     free Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 231.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Sci+Rep 2017 ; 7 (ä): ä Nephropedia Template TP {{tp|p=28262704|t=2017. IL-33/ST2 immune responses to respiratory bacteria in pediatric asthma |pdf=|usr=}}{{28262704}} gab.com Text IL-33/ST2 immune responses to respiratory bacteria in pediatric asthma JO: Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=28262704 #FOAvip Here we investigated the relationship between local bacterial colonization and anti-bacterial immune responses in pre-school asthmatic and control children within the EU-wide study PreDicta. In this cohort of pre-school asthmatic children, nasopharyngeal colonization with Gram-negative bacteria such as Haemophilus influenzae and Moraxella catarrhalis was found to be associated with the highest interferon beta (IFN?) and IL-33 levels in the nasal pharyngeal fluids (NPF). IL33R-ST2 was found induced in the blood of asthmatic children with additional Gram?+?bacteria in the nasopharynx (Gr+/?). Furthermore, asthmatic children had more episodes of infection that required antibiotic therapy than the control group. Treatment with antibiotics associated with reduced ST2 in blood cells of both asthmatic and control children and reduced IL-33 levels in the airways of asthmatic children. In the absence of Staphylococcus (S.) aureus in NPF, antibiotic therapy associated with decreased IL-33 levels in the NPF and lower ST2 values in the blood of control children but not of asthmatic children. These data suggest that, in asthmatic children, Gram- bacteria, which persist after antibiotic therapy, contributes to IL-33 locally and associated with Gr?+?bacteria colonization in the airways, inhibited IFN-? and in the absence of Staphylococcus (S.) aureus, induced ST2 bearing cells in their blood. Twit Text FOAVip IL-33/ST2 immune responses to respiratory bacteria in pediatric asthma ????Sci Rep http://www.kidney.de/pget.php?&tw=1&pmid=28262704 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28262704 #FOAvip English Wikipedia <ref>{{Cite pmid|28262704}}</ref> IL-33/ST2 immune responses to respiratory bacteria in pediatric asthma #MMPMID28262704 Hentschke I; Graser A; Melichar VO; Kiefer A; Zimmermann T; Kroß B; Haag P; Xepapadaki P; Papadopoulos NG; Bogdan C; Finotto S Sci Rep 2017[]; 7 (ä): ä PMID28262704show ga Here we investigated the relationship between local bacterial colonization and anti-bacterial immune responses in pre-school asthmatic and control children within the EU-wide study PreDicta. In this cohort of pre-school asthmatic children, nasopharyngeal colonization with Gram-negative bacteria such as Haemophilus influenzae and Moraxella catarrhalis was found to be associated with the highest interferon beta (IFN?) and IL-33 levels in the nasal pharyngeal fluids (NPF). IL33R-ST2 was found induced in the blood of asthmatic children with additional Gram?+?bacteria in the nasopharynx (Gr+/?). Furthermore, asthmatic children had more episodes of infection that required antibiotic therapy than the control group. Treatment with antibiotics associated with reduced ST2 in blood cells of both asthmatic and control children and reduced IL-33 levels in the airways of asthmatic children. In the absence of Staphylococcus (S.) aureus in NPF, antibiotic therapy associated with decreased IL-33 levels in the NPF and lower ST2 values in the blood of control children but not of asthmatic children. These data suggest that, in asthmatic children, Gram- bacteria, which persist after antibiotic therapy, contributes to IL-33 locally and associated with Gr?+?bacteria colonization in the airways, inhibited IFN-? and in the absence of Staphylococcus (S.) aureus, induced ST2 bearing cells in their blood. äIL-33/ST2 immune responses to respiratory bacteria in pediatric asthma(epmc).pdf DeepDyve Pubget Overpricing