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10.1038/srep43957

http://scihub22266oqcxt.onion/10.1038/srep43957
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C5338273!5338273!28262748
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suck abstract from ncbi


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pmid28262748      Sci+Rep 2017 ; 7 (ä): ä
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  • Diagnostic implication of fibrin degradation products and D-dimer in aortic dissection #MMPMID28262748
  • Dong J; Duan X; Feng R; Zhao Z; Feng X; Lu Q; Jing Q; Zhou J; Bao J; Jing Z
  • Sci Rep 2017[]; 7 (ä): ä PMID28262748show ga
  • Fibrin degradation products (FDP) and D-dimer have been considered to be involved in many vascular diseases. In this study we aimed to explore the diagnostic implication of FDP and D-dimer in aortic dissection patients. 202 aortic dissection patients were collected as the case group, 150 patients with other cardiovascular diseases, including myocardial infarction (MI, n?=?45), pulmonary infarction (n?=?51) and abdominal aortic aneurysm (n?=?54) were collected as non-dissection group, and 27 healthy people were in the blank control group. The FDP and D-dimer levels were detected with immune nephelometry. Logist regression analysis was performed to evaluate the influence of FDP and D-dimer for the aortic dissection patients. ROC curve was used to determine the diagnostic value of FDP and D-dimer. The FDP and D-dimer levels were significantly higher in aortic dissection patients than in non-dissection patients and the healthy controls. FDP and D-dimer were both the risk factors for patients with aortic dissection. From the ROC analysis, diagnostic value of FDP and D-dimer were not high to distinguish aortic dissection patients from the non-dissection patients. However FDP and D-dimer could be valuable diagnostic marker to differentiate aortic dissection patients and healthy controls with both AUC 0.863.
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