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2017 ; 2017
(ä): 7656418
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Combination of Navigated Macular Laser Photocoagulation and Anti-VEGF Therapy:
Precise Treatment for Macular Edema under Dry Retinal Conditions
#MMPMID28316837
Boiko EV
; Maltsev DS
J Ophthalmol
2017[]; 2017
(ä): 7656418
PMID28316837
show ga
Purpose. To compare the controllability of navigated macular laser
photocoagulation (MLP) in dry versus edematous retina and validate that
pretreatment diagnostic images can be used as basis for navigated MLP after the
macular edema (ME) has been resolved. Materials and Methods. Group 1 was divided
into subgroup 1 (dry retina MLP) and subgroup 2 (MLP in ME) for comparisons of
laser-burn diameters. In group 2, the areas and locations of ME before an
intravitreal injection of anti-VEGF (IVAV) were compared with those of recurrent
ME. Results. The average actual diameter as percentage of planned diameter of
laser burn in subgroup 1 (11 DME eyes, 6 BRVO eyes) versus subgroup 2 (5 DME
eyes, 8 BRVO eyes) was 115.1?±?9.1% versus 167.2?±?13.8% (based on retro-mode
scanning laser ophthalmoscopy), and 118.1?±?14.8% versus 176.1?±?11.6% (based on
OCT) (p < 0.001). In group 2 (6 DME eyes, 6 BRVO eyes), difference in mean ME
area before IVAV and that in recurrent edema was insignificant (p > 0.05).
Conclusion. The controllability of navigated MLP in dry retina is improved
compared to edematous retina. This study validates that pretreatment diagnostic
images can be used as basis for navigated MLP after the edema has been resolved.