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10.1155/2017/9671604 http://scihub22266oqcxt.onion/10.1155/2017/9671604 C5337389!5337389!28299345     free     free     free Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534 Deprecated: Implicit conversion from float 217.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       J+Immunol+Res 2017 ; 2017 (ä): ä Nephropedia Template TP {{tp|p=28299345|t=2017. Neutrophils and Immunity: From Bactericidal Action to Being Conquered |pdf=|usr=}}{{28299345}} gab.com Text Neutrophils and Immunity: From Bactericidal Action to Being Conquered JO: J Immunol Res http://www.kidney.de/pget.php?&tw=1&pmid=28299345 #FOAvip The neutrophil is the major phagocyte and the final effector cell of the innate immunity, with a primary role in the clearance of extracellular pathogens. Using the broad array of cytokines, extracellular traps, and effector molecules as the humoral arm, neutrophils play a crucial role in the host defense against pathogen infections. On the other hand, the pathogen has the capacity to overcome neutrophil-mediated host defense to establish infection causing human disease. Pathogens, such as S. aureus, have the potential to thwart neutrophil chemotaxis and phagocytosis and thereby succeed in evading killing by neutrophils. Furthermore, S. aureus surviving within neutrophils promotes neutrophil cytolysis, resulting in the release of host-derived molecules that promote local inflammation. Here, we provide a detailed overview of the mechanisms by which neutrophils kill the extracellular pathogens and how pathogens evade neutrophils degradation. This review will provide insights that might be useful for the development of novel therapies against infections caused by antibiotic resistant pathogens. Twit Text FOAVip Neutrophils and Immunity: From Bactericidal Action to Being Conquered ????J Immunol Res http://www.kidney.de/pget.php?&tw=1&pmid=28299345 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=28299345 #FOAvip English Wikipedia <ref>{{Cite pmid|28299345}}</ref> Neutrophils and Immunity: From Bactericidal Action to Being Conquered #MMPMID28299345 Teng TS; Ji Al; Ji XY; Li YZ J Immunol Res 2017[]; 2017 (ä): ä PMID28299345show ga The neutrophil is the major phagocyte and the final effector cell of the innate immunity, with a primary role in the clearance of extracellular pathogens. Using the broad array of cytokines, extracellular traps, and effector molecules as the humoral arm, neutrophils play a crucial role in the host defense against pathogen infections. On the other hand, the pathogen has the capacity to overcome neutrophil-mediated host defense to establish infection causing human disease. Pathogens, such as S. aureus, have the potential to thwart neutrophil chemotaxis and phagocytosis and thereby succeed in evading killing by neutrophils. Furthermore, S. aureus surviving within neutrophils promotes neutrophil cytolysis, resulting in the release of host-derived molecules that promote local inflammation. Here, we provide a detailed overview of the mechanisms by which neutrophils kill the extracellular pathogens and how pathogens evade neutrophils degradation. This review will provide insights that might be useful for the development of novel therapies against infections caused by antibiotic resistant pathogens. äNeutrophils and Immunity: From Bactericidal Action to Being Conquered (epmc).pdf DeepDyve Pubget Overpricing