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10.1038/nrc.2016.40 http://scihub22266oqcxt.onion/10.1038/nrc.2016.40 C5336345!5336345!27220482     free     free     free Deprecated: Implicit conversion from float 209.6 to int loses precision in C:\Inetpub\vhosts\kidney.de\httpdocs\pget.php on line 534       Nat+Rev+Cancer 2016 ; 16 (6): 387-98 Nephropedia Template TP {{tp|p=27220482|t=2016. Mechanisms of Human Lymphoid Chromosomal Translocations |pdf=|usr=}}{{27220482}} gab.com Text Mechanisms of Human Lymphoid Chromosomal Translocations JO: Nat Rev Cancer http://www.kidney.de/pget.php?&tw=1&pmid=27220482 #FOAvip Analysis of human chromosomal translocation sequence locations has yielded valuable clues about the mechanism of the translocations and their timing. Biochemical work on the mechanisms of DNA breakage and rejoining permits formulation of a detailed model of the human chromosomal translocation process in lymphoid neoplasms. Most human lymphomas are derived from B cells in which the break is initiated by activation-induced deaminase (AID). The partner locus in many cases is located at one of the antigen receptor loci, and this break is generated by the RAG complex or by AID. After breakage, the joining process typically occurs by nonhomologous DNA end joining (NHEJ). Some of the insights into this mechanism also apply to nonlymphoid neoplasms. Twit Text FOAVip Mechanisms of Human Lymphoid Chromosomal Translocations ????Nat Rev Cancer http://www.kidney.de/pget.php?&tw=1&pmid=27220482 #FOAvip Twit Text # Free Paper on # # # # # LINK http://www.kidney.de/pget.php?&tw=1&pmid=27220482 #FOAvip English Wikipedia <ref>{{Cite pmid|27220482}}</ref> Mechanisms of Human Lymphoid Chromosomal Translocations #MMPMID27220482 Lieber MR Nat Rev Cancer 2016[May]; 16 (6): 387-98 PMID27220482show ga Analysis of human chromosomal translocation sequence locations has yielded valuable clues about the mechanism of the translocations and their timing. Biochemical work on the mechanisms of DNA breakage and rejoining permits formulation of a detailed model of the human chromosomal translocation process in lymphoid neoplasms. Most human lymphomas are derived from B cells in which the break is initiated by activation-induced deaminase (AID). The partner locus in many cases is located at one of the antigen receptor loci, and this break is generated by the RAG complex or by AID. After breakage, the joining process typically occurs by nonhomologous DNA end joining (NHEJ). Some of the insights into this mechanism also apply to nonlymphoid neoplasms. äMechanisms of Human Lymphoid Chromosomal Translocations (epmc).pdf DeepDyve Pubget Overpricing